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Site-Specific Glycan-Masking/Unmasking Hemagglutinin Antigen Design to Elicit Broadly Neutralizing and Stem-Binding Antibodies Against Highly Pathogenic Avian Influenza H5N1 Virus Infections

The highly pathogenic avian influenza (HPAI) H5N1 viruses with the capability of transmission from birds to humans have a serious impact on public health. To date, HPAI H5N1 viruses have evolved into ten antigenically distinct clades that could cause a mismatch of vaccine strains and reduce vaccine...

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Detalles Bibliográficos
Autores principales:	Chen, Ting-Hsuan, Yang, Ya-Lin, Jan, Jia-Tsrong, Chen, Chung-Chu, Wu, Suh-Chin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317614/ https://www.ncbi.nlm.nih.gov/pubmed/34335603 http://dx.doi.org/10.3389/fimmu.2021.692700

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