Cargando…

Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation

PURPOSE OF REVIEW: Artificial intelligence (AI), machine learning, and technology-enabled remote patient care have evolved rapidly and have now been incorporated into many aspects of medical care. Transplantation is fortunate to have large data sets upon which machine learning algorithms can be cons...

Descripción completa

Detalles Bibliográficos
Autores principales: Schwantes, Issac R., Axelrod, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317681/
https://www.ncbi.nlm.nih.gov/pubmed/34341714
http://dx.doi.org/10.1007/s40472-021-00336-z
_version_ 1783730115858923520
author Schwantes, Issac R.
Axelrod, David A.
author_facet Schwantes, Issac R.
Axelrod, David A.
author_sort Schwantes, Issac R.
collection PubMed
description PURPOSE OF REVIEW: Artificial intelligence (AI), machine learning, and technology-enabled remote patient care have evolved rapidly and have now been incorporated into many aspects of medical care. Transplantation is fortunate to have large data sets upon which machine learning algorithms can be constructed. AI are now available to improve pretransplant management, donor selection, and post-operative management of transplant patients. RECENT FINDINGS: Changes in patient and donor characteristics warrant new approaches to listing and organ acceptance practices. Machine learning has been employed to optimize donor selection to identify patients likely to benefit from transplantation of higher risk organs, increasing organ discard and reducing waitlist mortality. These models have greater precisions and predictive ability than currently employed metrics including the Kidney Donor Profile Index and the expected posttransplant survival models. After transplant, AI tools have been developed to optimize immunosuppression management, track patients adherence, and assess graft survival. SUMMARY: AI and technology-enabled management tools are now available throughout the transplant journey. Unfortunately, those are frequently not available at the point of decision (patient listing, organ acceptance, posttransplant clinic), limiting utilization. Incorporation of these tools into the EMR, the Donor Net® organ offer system, and mobile devices is vital to ensure widespread adoption.
format Online
Article
Text
id pubmed-8317681
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-83176812021-07-29 Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation Schwantes, Issac R. Axelrod, David A. Curr Transplant Rep Expanding Role of Technology in Organ Transplant (D Axelrod and J Scalea, Section Editors) PURPOSE OF REVIEW: Artificial intelligence (AI), machine learning, and technology-enabled remote patient care have evolved rapidly and have now been incorporated into many aspects of medical care. Transplantation is fortunate to have large data sets upon which machine learning algorithms can be constructed. AI are now available to improve pretransplant management, donor selection, and post-operative management of transplant patients. RECENT FINDINGS: Changes in patient and donor characteristics warrant new approaches to listing and organ acceptance practices. Machine learning has been employed to optimize donor selection to identify patients likely to benefit from transplantation of higher risk organs, increasing organ discard and reducing waitlist mortality. These models have greater precisions and predictive ability than currently employed metrics including the Kidney Donor Profile Index and the expected posttransplant survival models. After transplant, AI tools have been developed to optimize immunosuppression management, track patients adherence, and assess graft survival. SUMMARY: AI and technology-enabled management tools are now available throughout the transplant journey. Unfortunately, those are frequently not available at the point of decision (patient listing, organ acceptance, posttransplant clinic), limiting utilization. Incorporation of these tools into the EMR, the Donor Net® organ offer system, and mobile devices is vital to ensure widespread adoption. Springer International Publishing 2021-07-28 2021 /pmc/articles/PMC8317681/ /pubmed/34341714 http://dx.doi.org/10.1007/s40472-021-00336-z Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Expanding Role of Technology in Organ Transplant (D Axelrod and J Scalea, Section Editors)
Schwantes, Issac R.
Axelrod, David A.
Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation
title Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation
title_full Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation
title_fullStr Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation
title_full_unstemmed Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation
title_short Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation
title_sort technology-enabled care and artificial intelligence in kidney transplantation
topic Expanding Role of Technology in Organ Transplant (D Axelrod and J Scalea, Section Editors)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317681/
https://www.ncbi.nlm.nih.gov/pubmed/34341714
http://dx.doi.org/10.1007/s40472-021-00336-z
work_keys_str_mv AT schwantesissacr technologyenabledcareandartificialintelligenceinkidneytransplantation
AT axelroddavida technologyenabledcareandartificialintelligenceinkidneytransplantation