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Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation
PURPOSE OF REVIEW: Artificial intelligence (AI), machine learning, and technology-enabled remote patient care have evolved rapidly and have now been incorporated into many aspects of medical care. Transplantation is fortunate to have large data sets upon which machine learning algorithms can be cons...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317681/ https://www.ncbi.nlm.nih.gov/pubmed/34341714 http://dx.doi.org/10.1007/s40472-021-00336-z |
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author | Schwantes, Issac R. Axelrod, David A. |
author_facet | Schwantes, Issac R. Axelrod, David A. |
author_sort | Schwantes, Issac R. |
collection | PubMed |
description | PURPOSE OF REVIEW: Artificial intelligence (AI), machine learning, and technology-enabled remote patient care have evolved rapidly and have now been incorporated into many aspects of medical care. Transplantation is fortunate to have large data sets upon which machine learning algorithms can be constructed. AI are now available to improve pretransplant management, donor selection, and post-operative management of transplant patients. RECENT FINDINGS: Changes in patient and donor characteristics warrant new approaches to listing and organ acceptance practices. Machine learning has been employed to optimize donor selection to identify patients likely to benefit from transplantation of higher risk organs, increasing organ discard and reducing waitlist mortality. These models have greater precisions and predictive ability than currently employed metrics including the Kidney Donor Profile Index and the expected posttransplant survival models. After transplant, AI tools have been developed to optimize immunosuppression management, track patients adherence, and assess graft survival. SUMMARY: AI and technology-enabled management tools are now available throughout the transplant journey. Unfortunately, those are frequently not available at the point of decision (patient listing, organ acceptance, posttransplant clinic), limiting utilization. Incorporation of these tools into the EMR, the Donor Net® organ offer system, and mobile devices is vital to ensure widespread adoption. |
format | Online Article Text |
id | pubmed-8317681 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-83176812021-07-29 Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation Schwantes, Issac R. Axelrod, David A. Curr Transplant Rep Expanding Role of Technology in Organ Transplant (D Axelrod and J Scalea, Section Editors) PURPOSE OF REVIEW: Artificial intelligence (AI), machine learning, and technology-enabled remote patient care have evolved rapidly and have now been incorporated into many aspects of medical care. Transplantation is fortunate to have large data sets upon which machine learning algorithms can be constructed. AI are now available to improve pretransplant management, donor selection, and post-operative management of transplant patients. RECENT FINDINGS: Changes in patient and donor characteristics warrant new approaches to listing and organ acceptance practices. Machine learning has been employed to optimize donor selection to identify patients likely to benefit from transplantation of higher risk organs, increasing organ discard and reducing waitlist mortality. These models have greater precisions and predictive ability than currently employed metrics including the Kidney Donor Profile Index and the expected posttransplant survival models. After transplant, AI tools have been developed to optimize immunosuppression management, track patients adherence, and assess graft survival. SUMMARY: AI and technology-enabled management tools are now available throughout the transplant journey. Unfortunately, those are frequently not available at the point of decision (patient listing, organ acceptance, posttransplant clinic), limiting utilization. Incorporation of these tools into the EMR, the Donor Net® organ offer system, and mobile devices is vital to ensure widespread adoption. Springer International Publishing 2021-07-28 2021 /pmc/articles/PMC8317681/ /pubmed/34341714 http://dx.doi.org/10.1007/s40472-021-00336-z Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Expanding Role of Technology in Organ Transplant (D Axelrod and J Scalea, Section Editors) Schwantes, Issac R. Axelrod, David A. Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation |
title | Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation |
title_full | Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation |
title_fullStr | Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation |
title_full_unstemmed | Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation |
title_short | Technology-Enabled Care and Artificial Intelligence in Kidney Transplantation |
title_sort | technology-enabled care and artificial intelligence in kidney transplantation |
topic | Expanding Role of Technology in Organ Transplant (D Axelrod and J Scalea, Section Editors) |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317681/ https://www.ncbi.nlm.nih.gov/pubmed/34341714 http://dx.doi.org/10.1007/s40472-021-00336-z |
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