Cargando…

Minimally Invasive Buccal Mucosa Dorsal Graft for Female Distal Urethroplasty

BACKGROUND: Female urethral stricture (FUS) represents a sporadic condition. There is a lack of data and standardized guidelines on diagnostics and therapeutics. Several surgical techniques have been described for FUS urethroplasty, among which the flap-based or graft-based ones are most reported. B...

Descripción completa

Detalles Bibliográficos
Autores principales: Berdondini, Elisa, Tosco, Lorenzo, Margara, Andrea, Giacobbe, Alessandro, Collura, Devis, Germinale, Federico, Kurti, Marisa, Muto, Gianluca, Muto, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317839/
https://www.ncbi.nlm.nih.gov/pubmed/34337493
http://dx.doi.org/10.1016/j.euros.2020.12.001
_version_ 1783730130334515200
author Berdondini, Elisa
Tosco, Lorenzo
Margara, Andrea
Giacobbe, Alessandro
Collura, Devis
Germinale, Federico
Kurti, Marisa
Muto, Gianluca
Muto, Giovanni
author_facet Berdondini, Elisa
Tosco, Lorenzo
Margara, Andrea
Giacobbe, Alessandro
Collura, Devis
Germinale, Federico
Kurti, Marisa
Muto, Gianluca
Muto, Giovanni
author_sort Berdondini, Elisa
collection PubMed
description BACKGROUND: Female urethral stricture (FUS) represents a sporadic condition. There is a lack of data and standardized guidelines on diagnostics and therapeutics. Several surgical techniques have been described for FUS urethroplasty, among which the flap-based or graft-based ones are most reported. Buccal mucosa graft (BMG) represents the gold standard for male urethroplasty, and this can theoretically be applied also to FUS treatment. OBJECTIVE: To describe and present preliminary results of a novel minimally invasive technique for buccal mucosa dorsal graft (mini-dorsal BMG) urethroplasty for the treatment of FUS. DESIGN, SETTING, AND PARTICIPANTS: This is a retrospective study on buccal mucosa dorsal graft urethroplasty for the treatment of FUS. SURGICAL PROCEDURE: Every patient was placed in lithotomic position. Two stiches were placed at 10 and 2 o’clock positions to facilitate the dorsal median urethrotomy. The margins of the incised dorsal urethra at the 12 o’clock position are then dissected from the periurethral tissue. This dissection results in an elliptical raw area between the edges of the urethra over the periurethral tissue. The harvested BMG was fixed with several quilting sutures, using 5-0 and 4-0 absorbable sutures, to cover the raw area. The margins of the graft were sutured to the edges of the incised urethra. MEASUREMENTS: A chart review was performed. RESULTS AND LIMITATIONS: Thirteen patients underwent the mini-dorsal-BMG technique. The median preoperative uroflow was 5.6 (3–13) ml/s, and the median postoperative value was 23.4 (14–58) ml/s. CONCLUSIONS: The mini-dorsal-BMG technique for the treatment of FUS gives good results with low complication rates. Other series and long-term follow-up are necessary to confirm the reproducibility of this technique. PATIENT SUMMARY: We present the technical aspects and the promising preliminary results of a novel surgical technique for the treatment of female urethral stricture by using the buccal mucosa to correct this invalidating disease.
format Online
Article
Text
id pubmed-8317839
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-83178392021-07-29 Minimally Invasive Buccal Mucosa Dorsal Graft for Female Distal Urethroplasty Berdondini, Elisa Tosco, Lorenzo Margara, Andrea Giacobbe, Alessandro Collura, Devis Germinale, Federico Kurti, Marisa Muto, Gianluca Muto, Giovanni Eur Urol Open Sci Surgery in Motion: Open Science BACKGROUND: Female urethral stricture (FUS) represents a sporadic condition. There is a lack of data and standardized guidelines on diagnostics and therapeutics. Several surgical techniques have been described for FUS urethroplasty, among which the flap-based or graft-based ones are most reported. Buccal mucosa graft (BMG) represents the gold standard for male urethroplasty, and this can theoretically be applied also to FUS treatment. OBJECTIVE: To describe and present preliminary results of a novel minimally invasive technique for buccal mucosa dorsal graft (mini-dorsal BMG) urethroplasty for the treatment of FUS. DESIGN, SETTING, AND PARTICIPANTS: This is a retrospective study on buccal mucosa dorsal graft urethroplasty for the treatment of FUS. SURGICAL PROCEDURE: Every patient was placed in lithotomic position. Two stiches were placed at 10 and 2 o’clock positions to facilitate the dorsal median urethrotomy. The margins of the incised dorsal urethra at the 12 o’clock position are then dissected from the periurethral tissue. This dissection results in an elliptical raw area between the edges of the urethra over the periurethral tissue. The harvested BMG was fixed with several quilting sutures, using 5-0 and 4-0 absorbable sutures, to cover the raw area. The margins of the graft were sutured to the edges of the incised urethra. MEASUREMENTS: A chart review was performed. RESULTS AND LIMITATIONS: Thirteen patients underwent the mini-dorsal-BMG technique. The median preoperative uroflow was 5.6 (3–13) ml/s, and the median postoperative value was 23.4 (14–58) ml/s. CONCLUSIONS: The mini-dorsal-BMG technique for the treatment of FUS gives good results with low complication rates. Other series and long-term follow-up are necessary to confirm the reproducibility of this technique. PATIENT SUMMARY: We present the technical aspects and the promising preliminary results of a novel surgical technique for the treatment of female urethral stricture by using the buccal mucosa to correct this invalidating disease. Elsevier 2021-01-06 /pmc/articles/PMC8317839/ /pubmed/34337493 http://dx.doi.org/10.1016/j.euros.2020.12.001 Text en © 2020 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Surgery in Motion: Open Science
Berdondini, Elisa
Tosco, Lorenzo
Margara, Andrea
Giacobbe, Alessandro
Collura, Devis
Germinale, Federico
Kurti, Marisa
Muto, Gianluca
Muto, Giovanni
Minimally Invasive Buccal Mucosa Dorsal Graft for Female Distal Urethroplasty
title Minimally Invasive Buccal Mucosa Dorsal Graft for Female Distal Urethroplasty
title_full Minimally Invasive Buccal Mucosa Dorsal Graft for Female Distal Urethroplasty
title_fullStr Minimally Invasive Buccal Mucosa Dorsal Graft for Female Distal Urethroplasty
title_full_unstemmed Minimally Invasive Buccal Mucosa Dorsal Graft for Female Distal Urethroplasty
title_short Minimally Invasive Buccal Mucosa Dorsal Graft for Female Distal Urethroplasty
title_sort minimally invasive buccal mucosa dorsal graft for female distal urethroplasty
topic Surgery in Motion: Open Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317839/
https://www.ncbi.nlm.nih.gov/pubmed/34337493
http://dx.doi.org/10.1016/j.euros.2020.12.001
work_keys_str_mv AT berdondinielisa minimallyinvasivebuccalmucosadorsalgraftforfemaledistalurethroplasty
AT toscolorenzo minimallyinvasivebuccalmucosadorsalgraftforfemaledistalurethroplasty
AT margaraandrea minimallyinvasivebuccalmucosadorsalgraftforfemaledistalurethroplasty
AT giacobbealessandro minimallyinvasivebuccalmucosadorsalgraftforfemaledistalurethroplasty
AT colluradevis minimallyinvasivebuccalmucosadorsalgraftforfemaledistalurethroplasty
AT germinalefederico minimallyinvasivebuccalmucosadorsalgraftforfemaledistalurethroplasty
AT kurtimarisa minimallyinvasivebuccalmucosadorsalgraftforfemaledistalurethroplasty
AT mutogianluca minimallyinvasivebuccalmucosadorsalgraftforfemaledistalurethroplasty
AT mutogiovanni minimallyinvasivebuccalmucosadorsalgraftforfemaledistalurethroplasty