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High Serine-arginine Protein Kinase 1 Expression with PTEN Loss Defines Aggressive Phenotype of Prostate Cancer Associated with Lethal Outcome and Decreased Overall Survival

BACKGROUND: Serine-arginine protein kinase 1 (SRPK1) has been implicated in prostate cancer (PCa) progression. However, its prognostic value and association with ERG and PTEN expression, two of the most common genetic alterations, have not been explored fully. OBJECTIVE: We assessed the prognostic v...

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Detalles Bibliográficos
Autores principales:	Abou-Ouf, Hatem, Assem, Hisham, Ghosh, Sunita, Karnes, R. Jeffrey, Stoletov, Konstantin, Palanisamy, Nallasivam, Lewis, John D., Bismar, Tarek A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Prostate Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317848/ https://www.ncbi.nlm.nih.gov/pubmed/34337483 http://dx.doi.org/10.1016/j.euros.2020.11.005

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