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Decreased ATM Protein Expression Is Substantiated with PTEN Loss in Defining Aggressive Phenotype of Prostate Cancer Associated with Lethal Disease

BACKGROUND: Ataxia Telangiectasia Mutated (ATM) serine/threonine protein kinase is a known tumor suppressor, involved in DNA damage repair. It has prognostic and predictive therapeutic implications and is associated with aggressive prostate cancer (PCa). OBJECTIVE: To investigate the prognostic valu...

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Detalles Bibliográficos
Autores principales:	Walker, Simon R., Abdelsalam, Ramy, Ghosh, Sunita, Livingstone, Julie, Palanisamy, Nallasivam, Boutros, Paul C., Yip, Steven M., Lees-Miller, Susan P., Bismar, Tarek A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Prostate Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317877/ https://www.ncbi.nlm.nih.gov/pubmed/34337539 http://dx.doi.org/10.1016/j.euros.2021.05.004

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