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Impact of IL-1β and the IL-1R antagonist on relapse risk and survival in AML patients undergoing immunotherapy for remission maintenance

Interleukin-1 beta (IL-1β), a pro-inflammatory cytokine, has been ascribed a role in the expansion of myeloid progenitors in acute myeloid leukemia (AML) and in promoting myeloid cell-induced suppression of lymphocyte-mediated immunity against malignant cells. This study aimed at defining the potent...

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Detalles Bibliográficos
Autores principales: Grauers Wiktorin, Hanna, Aydin, Ebru, Christenson, Karin, Issdisai, Nuttida, Thorén, Fredrik B., Hellstrand, Kristoffer, Martner, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317920/
https://www.ncbi.nlm.nih.gov/pubmed/34367728
http://dx.doi.org/10.1080/2162402X.2021.1944538