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Age-Related Differences in Auditory Cortex Activity During Spoken Word Recognition

Understanding spoken words requires the rapid matching of a complex acoustic stimulus with stored lexical representations. The degree to which brain networks supporting spoken word recognition are affected by adult aging remains poorly understood. In the current study we used fMRI to measure the bra...

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Autores principales: Rogers, Chad S., Jones, Michael S., McConkey, Sarah, Spehar, Brent, Van Engen, Kristin J., Sommers, Mitchell S., Peelle, Jonathan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MIT Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318202/
https://www.ncbi.nlm.nih.gov/pubmed/34327333
http://dx.doi.org/10.1162/nol_a_00021
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author Rogers, Chad S.
Jones, Michael S.
McConkey, Sarah
Spehar, Brent
Van Engen, Kristin J.
Sommers, Mitchell S.
Peelle, Jonathan E.
author_facet Rogers, Chad S.
Jones, Michael S.
McConkey, Sarah
Spehar, Brent
Van Engen, Kristin J.
Sommers, Mitchell S.
Peelle, Jonathan E.
author_sort Rogers, Chad S.
collection PubMed
description Understanding spoken words requires the rapid matching of a complex acoustic stimulus with stored lexical representations. The degree to which brain networks supporting spoken word recognition are affected by adult aging remains poorly understood. In the current study we used fMRI to measure the brain responses to spoken words in two conditions: an attentive listening condition, in which no response was required, and a repetition task. Listeners were 29 young adults (aged 19–30 years) and 32 older adults (aged 65–81 years) without self-reported hearing difficulty. We found largely similar patterns of activity during word perception for both young and older adults, centered on the bilateral superior temporal gyrus. As expected, the repetition condition resulted in significantly more activity in areas related to motor planning and execution (including the premotor cortex and supplemental motor area) compared to the attentive listening condition. Importantly, however, older adults showed significantly less activity in probabilistically defined auditory cortex than young adults when listening to individual words in both the attentive listening and repetition tasks. Age differences in auditory cortex activity were seen selectively for words (no age differences were present for 1-channel vocoded speech, used as a control condition), and could not be easily explained by accuracy on the task, movement in the scanner, or hearing sensitivity (available on a subset of participants). These findings indicate largely similar patterns of brain activity for young and older adults when listening to words in quiet, but suggest less recruitment of auditory cortex by the older adults.
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spelling pubmed-83182022021-07-28 Age-Related Differences in Auditory Cortex Activity During Spoken Word Recognition Rogers, Chad S. Jones, Michael S. McConkey, Sarah Spehar, Brent Van Engen, Kristin J. Sommers, Mitchell S. Peelle, Jonathan E. Neurobiol Lang (Camb) Research Articles Understanding spoken words requires the rapid matching of a complex acoustic stimulus with stored lexical representations. The degree to which brain networks supporting spoken word recognition are affected by adult aging remains poorly understood. In the current study we used fMRI to measure the brain responses to spoken words in two conditions: an attentive listening condition, in which no response was required, and a repetition task. Listeners were 29 young adults (aged 19–30 years) and 32 older adults (aged 65–81 years) without self-reported hearing difficulty. We found largely similar patterns of activity during word perception for both young and older adults, centered on the bilateral superior temporal gyrus. As expected, the repetition condition resulted in significantly more activity in areas related to motor planning and execution (including the premotor cortex and supplemental motor area) compared to the attentive listening condition. Importantly, however, older adults showed significantly less activity in probabilistically defined auditory cortex than young adults when listening to individual words in both the attentive listening and repetition tasks. Age differences in auditory cortex activity were seen selectively for words (no age differences were present for 1-channel vocoded speech, used as a control condition), and could not be easily explained by accuracy on the task, movement in the scanner, or hearing sensitivity (available on a subset of participants). These findings indicate largely similar patterns of brain activity for young and older adults when listening to words in quiet, but suggest less recruitment of auditory cortex by the older adults. MIT Press 2020-10-01 /pmc/articles/PMC8318202/ /pubmed/34327333 http://dx.doi.org/10.1162/nol_a_00021 Text en © 2020 Massachusetts Institute of Technology https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. For a full description of the license, please visit https://creativecommons.org/licenses/by/4.0/legalcode (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Articles
Rogers, Chad S.
Jones, Michael S.
McConkey, Sarah
Spehar, Brent
Van Engen, Kristin J.
Sommers, Mitchell S.
Peelle, Jonathan E.
Age-Related Differences in Auditory Cortex Activity During Spoken Word Recognition
title Age-Related Differences in Auditory Cortex Activity During Spoken Word Recognition
title_full Age-Related Differences in Auditory Cortex Activity During Spoken Word Recognition
title_fullStr Age-Related Differences in Auditory Cortex Activity During Spoken Word Recognition
title_full_unstemmed Age-Related Differences in Auditory Cortex Activity During Spoken Word Recognition
title_short Age-Related Differences in Auditory Cortex Activity During Spoken Word Recognition
title_sort age-related differences in auditory cortex activity during spoken word recognition
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318202/
https://www.ncbi.nlm.nih.gov/pubmed/34327333
http://dx.doi.org/10.1162/nol_a_00021
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