Cargando…

Therapeutic Effect of IL-4 Receptor-Targeting Pro-Apoptotic Peptide (AP1-ELP-KLAK) in Glioblastoma Tumor Model

BACKGROUND: Thermal-responsive self-assembled elastin-like polypeptide (ELP)-based nanoparticles are an emerging platform for controlled delivery of therapeutic peptides, proteins and small molecular drugs. The antitumor effect of bioengineered chimeric polypeptide AP1-ELP-KLAK containing an interle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sarangthem, Vijaya, Yi, Aena, Kim, Yunjae, Rehemtulla, Alnawaz, Lee, Byung-Heon, Jeon, Young Hyun, Singh, Thoudam Debraj, Park, Rang-Woon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318221/ https://www.ncbi.nlm.nih.gov/pubmed/34335025 http://dx.doi.org/10.2147/IJN.S316388

Ejemplares similares

Multivalent Targeting Based Delivery of Therapeutic Peptide using AP1-ELP Carrier for Effective Cancer Therapy
por: Sarangthem, Vijaya, et al.
Publicado: (2016)

Effects of molecular weight and structural conformation of multivalent-based elastin-like polypeptides on tumor accumulation and tissue biodistribution
por: Sarangthem, Vijaya, et al.
Publicado: (2020)

Application of Bld-1-Embedded Elastin-Like Polypeptides in Tumor Targeting
por: Sarangthem, Vijaya, et al.
Publicado: (2018)

Construction and Application of Elastin Like Polypeptide Containing IL-4 Receptor Targeting Peptide
por: Sarangthem, Vijaya, et al.
Publicado: (2013)

Development of elastin-like polypeptide for targeted specific gene delivery in vivo
por: Yi, Aena, et al.
Publicado: (2020)

Application of bioengineered elastin-like polypeptide-based system for targeted gene delivery in tumor cells()
por: Yi, Aena, et al.
Publicado: (2022)

Application of Bio-Active Elastin-like Polypeptide on Regulation of Human Mesenchymal Stem Cell Behavior
por: Sarangthem, Vijaya, et al.
Publicado: (2022)

Unfolding of Imminent Bio-Signatures in the Prognosis of Thyroid Cancer; The Emergence of Estrogen Related Receptor Gamma (ERRγ) as a Hurricane
por: Gulwani, Deepak, et al.
Publicado: (2023)

An Inverse Agonist of Estrogen-Related Receptor Gamma, GSK5182, Enhances Na(+)/I(−) Symporter Function in Radioiodine-Refractory Papillary Thyroid Cancer Cells
por: Singh, Thoudam Debraj, et al.
Publicado: (2023)

ELPS helps!
por: Valaiyapathi, Rajalakshmi, et al.
Publicado: (2021)

Imaging Proteolytic Activities in Mouse Models of Cancer
por: Pal, Anupama, et al.
Publicado: (2018)

The Arabidopsis Elongator Subunit ELP3 and ELP4 Confer Resistance to Bacterial Speck in Tomato
por: Pereira, Juliana A., et al.
Publicado: (2018)

Lending an ‘ELPing hand to tumor initiation
por: Rich, Jeremy
Publicado: (2015)

Characterization of fibroblast growth factor receptor 2 overexpression in the human breast cancer cell line SUM-52PE
por: Tannheimer, Stacey L, et al.
Publicado: (2000)

Novel molecular imaging platform for monitoring oncological kinases
por: Nyati, Shyam, et al.
Publicado: (2010)

The Arabidopsis ELP3/ELO3 and ELP4/ELO1 genes enhance disease resistance in Fragaria vesca L.
por: Silva, Katchen Julliany P., et al.
Publicado: (2017)

PPARγ regulated CIDEA affects pro-apoptotic responses in glioblastoma
por: Chatterjee, A, et al.
Publicado: (2015)

The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma
por: Ozyerli-Goknar, Ezgi, et al.
Publicado: (2019)

Noninvasive Bioluminescence Imaging of AKT Kinase Activity in Subcutaneous and Orthotopic NSCLC Xenografts: Correlation of AKT Activity with Tumor Growth Kinetics()
por: Suchowski, Karina, et al.
Publicado: (2017)

Budding uninhibited by benzimidazoles-1 (BUB1) regulates EGFR signaling by reducing EGFR internalization
por: Nyati, Shyam, et al.
Publicado: (2023)

Insights into the Bioinformatics and Transcriptional Analysis of the Elongator Complexes (ELPs) Gene Family of Wheat: TaELPs Contribute to Wheat Abiotic Stress Tolerance and Leaf Senescence
por: Guo, Feng, et al.
Publicado: (2023)

Exogenous lipoid pneumonia (ELP): when radiologist makes the difference
por: Rea, G, et al.
Publicado: (2016)

Immunohistochemistry as a tool to identify ELP1-associated medulloblastoma
por: Tauziède-Espariat, Arnault, et al.
Publicado: (2022)

MEDB-84. The French experience of ELP1-related medulloblastomas
por: Tauziède-Espariat, Arnault, et al.
Publicado: (2022)

Inducing Oncoprotein Degradation to Improve Targeted Cancer Therapy()
por: Ray, Dipankar, et al.
Publicado: (2015)

Ebi/AP-1 Suppresses Pro-Apoptotic Genes Expression and Permits Long-Term Survival of Drosophila Sensory Neurons
por: Lim, Young-Mi, et al.
Publicado: (2012)

A Requirement for ZAK Kinase Activity in Canonical TGF-β Signaling()
por: Nyati, Shyam, et al.
Publicado: (2016)

The Pro-Apoptotic Effect of Silica Nanoparticles Depends on Their Size and Dose, as Well as the Type of Glioblastoma Cells
por: Krętowski, Rafał, et al.
Publicado: (2021)

Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes
por: Xu, Shili, et al.
Publicado: (2019)

Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine
por: Ladang, Aurélie, et al.
Publicado: (2015)

Elongator Subunit 3 (Elp3) Is Required for Zebrafish Trunk Development
por: Rojas-Benítez, Diego, et al.
Publicado: (2020)

Temperature Effect on the Adsorption and Volumetric Properties of Aqueous Solutions of Kolliphor(®)ELP
por: Szymczyk, Katarzyna, et al.
Publicado: (2020)

A dose-escalating toxicology study of the candidate biologic ELP-VEGF
por: Waller, Jamarius P., et al.
Publicado: (2021)

Elp1 is required for development of visceral sensory peripheral and central circuitry
por: Tolman, Zariah, et al.
Publicado: (2022)

Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model
por: Donadon, Irving, et al.
Publicado: (2018)

The pro-apoptotic Bcl-2 family member Harakiri (HRK) induces cell death in glioblastoma multiforme
por: Kaya-Aksoy, Ezgi, et al.
Publicado: (2019)

Cancer research in India: Challenges & opportunities
por: Singh, Mayank, et al.
Publicado: (2018)

Evaluation of Concurrent Radiation, Temozolomide and ABT-888 Treatment Followed by Maintenance Therapy with Temozolomide and ABT-888 in a Genetically Engineered Glioblastoma Mouse Model
por: Lemasson, Benjamin, et al.
Publicado: (2016)

A lipid-associated macrophage lineage rewires the spatial landscape of adipose tissue in early obesity
por: Stansbury, Cooper M., et al.
Publicado: (2023)

Ikbkap/Elp1 Deficiency Causes Male Infertility by Disrupting Meiotic Progression
por: Lin, Fu-Jung, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3fvupvddd6q8ho2enh2bhh3lci