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Improving lung compliance by external compression of the chest wall

As exemplified by prone positioning, regional variations of lung and chest wall properties provide possibilities for modifying transpulmonary pressures and suggest that clinical interventions related to the judicious application of external pressure may yield benefit. Recent observations made in lat...

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Detalles Bibliográficos
Autores principales: Marini, John J., Gattinoni, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318320/
https://www.ncbi.nlm.nih.gov/pubmed/34321060
http://dx.doi.org/10.1186/s13054-021-03700-8
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author Marini, John J.
Gattinoni, Luciano
author_facet Marini, John J.
Gattinoni, Luciano
author_sort Marini, John J.
collection PubMed
description As exemplified by prone positioning, regional variations of lung and chest wall properties provide possibilities for modifying transpulmonary pressures and suggest that clinical interventions related to the judicious application of external pressure may yield benefit. Recent observations made in late-phase patients with severe ARDS caused by COVID-19 (C-ARDS) have revealed unexpected mechanical responses to local chest wall compressions over the sternum and abdomen in the supine position that challenge the clinician’s assumptions and conventional bedside approaches to lung protection. These findings appear to open avenues for mechanism-defining research investigation with possible therapeutic implications for all forms and stages of ARDS.
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spelling pubmed-83183202021-07-29 Improving lung compliance by external compression of the chest wall Marini, John J. Gattinoni, Luciano Crit Care Review As exemplified by prone positioning, regional variations of lung and chest wall properties provide possibilities for modifying transpulmonary pressures and suggest that clinical interventions related to the judicious application of external pressure may yield benefit. Recent observations made in late-phase patients with severe ARDS caused by COVID-19 (C-ARDS) have revealed unexpected mechanical responses to local chest wall compressions over the sternum and abdomen in the supine position that challenge the clinician’s assumptions and conventional bedside approaches to lung protection. These findings appear to open avenues for mechanism-defining research investigation with possible therapeutic implications for all forms and stages of ARDS. BioMed Central 2021-07-28 /pmc/articles/PMC8318320/ /pubmed/34321060 http://dx.doi.org/10.1186/s13054-021-03700-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Marini, John J.
Gattinoni, Luciano
Improving lung compliance by external compression of the chest wall
title Improving lung compliance by external compression of the chest wall
title_full Improving lung compliance by external compression of the chest wall
title_fullStr Improving lung compliance by external compression of the chest wall
title_full_unstemmed Improving lung compliance by external compression of the chest wall
title_short Improving lung compliance by external compression of the chest wall
title_sort improving lung compliance by external compression of the chest wall
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318320/
https://www.ncbi.nlm.nih.gov/pubmed/34321060
http://dx.doi.org/10.1186/s13054-021-03700-8
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