Tapering of prescribed opioids in patients with long-term non-malignant pain (TOPIO)—efficacy and effects on pain, pain cognitions, and quality of life: a study protocol for a randomized controlled clinical trial with a 12-month follow-up

BACKGROUND: Opioids are still widely prescribed to long-term pain patients although they are no longer recommended for long-term treatments due to poor evidence for long-term efficacy, risks of serious side effects, and the possibility of inducing opioid hyperalgesia. In a Cochrane study from 2017,...

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Detalles Bibliográficos
Autores principales: Henrik, Grelz, Patrik, Midlöv, Anders, Håkansson, Ulf, Jakobsson, Marcelo, Rivano Fischer, Åsa, Ringqvist
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318331/
https://www.ncbi.nlm.nih.gov/pubmed/34321058
http://dx.doi.org/10.1186/s13063-021-05449-5

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