Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

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Rationally designed protein subunit vaccines are being developed for a variety of viruses including influenza, RSV, SARS-CoV-2, and HIV. These vaccines are based on stabilized versions of the primary targets of neutralizing antibodies on the viral surface, namely, viral fusion glycoproteins. While t...

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Detalles Bibliográficos
Autores principales: Turner, Hannah L., Andrabi, Raiees, Cottrell, Christopher A., Richey, Sara T., Song, Ge, Callaghan, Sean, Anzanello, Fabio, Moyer, Tyson J., Abraham, Wuhbet, Melo, Mariane, Silva, Murillo, Scaringi, Nicole, Rakasz, Eva G., Sattentau, Quentin J., Irvine, Darrell J., Burton, Dennis R., Ward, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318364/
https://www.ncbi.nlm.nih.gov/pubmed/34321200
http://dx.doi.org/10.1126/sciadv.abh2791
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