Multimodality assessment of heart failure with preserved ejection fraction skeletal muscle reveals differences in the machinery of energy fuel metabolism

AIMS: Skeletal muscle (SkM) abnormalities may impact exercise capacity in patients with heart failure with preserved ejection fraction (HFpEF). We sought to quantify differences in SkM oxidative phosphorylation capacity (OxPhos), fibre composition, and the SkM proteome between HFpEF, hypertensive (H...

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Detalles Bibliográficos
Autores principales: Zamani, Payman, Proto, Elizabeth A., Wilson, Neil, Fazelinia, Hossein, Ding, Hua, Spruce, Lynn A., Davila, Antonio, Hanff, Thomas C., Mazurek, Jeremy A., Prenner, Stuart B., Desjardins, Benoit, Margulies, Kenneth B., Kelly, Daniel P., Arany, Zoltan, Doulias, Paschalis‐Thomas, Elrod, John W., Allen, Mitchell E., McCormack, Shana E., Schur, Gayatri Maria, D'Aquilla, Kevin, Kumar, Dushyant, Thakuri, Deepa, Prabhakaran, Karthik, Langham, Michael C., Poole, David C., Seeholzer, Steven H., Reddy, Ravinder, Ischiropoulos, Harry, Chirinos, Julio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318475/
https://www.ncbi.nlm.nih.gov/pubmed/33991175
http://dx.doi.org/10.1002/ehf2.13329

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