The Akt pathway mediates the protective effects of myeloid differentiation protein 1 in pathological cardiac remodelling

AIMS: Myeloid differentiation protein 1 (MD1) was shown to ameliorate pressure overload‐induced cardiac hypertrophy and fibrosis by negatively regulating the MEK–ERK1/2 and NF‐κB pathways. However, whether MD1 modulates cardiac function and whether the Akt pathway mediates the benefits of MD1 in pre...

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Detalles Bibliográficos
Autores principales: Peng, Jianye, Zeng, Gaofeng, Zhong, Peng, Wang, Guangji, Lei, ChangCheng, Tian, Guoping, Chen, Jingsong, Wu, Jianfeng, Shen, Caijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318477/
https://www.ncbi.nlm.nih.gov/pubmed/34041859
http://dx.doi.org/10.1002/ehf2.13447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318477/
https://www.ncbi.nlm.nih.gov/pubmed/34041859
http://dx.doi.org/10.1002/ehf2.13447

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