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The Akt pathway mediates the protective effects of myeloid differentiation protein 1 in pathological cardiac remodelling

AIMS: Myeloid differentiation protein 1 (MD1) was shown to ameliorate pressure overload‐induced cardiac hypertrophy and fibrosis by negatively regulating the MEK–ERK1/2 and NF‐κB pathways. However, whether MD1 modulates cardiac function and whether the Akt pathway mediates the benefits of MD1 in pre...

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Detalles Bibliográficos
Autores principales:	Peng, Jianye, Zeng, Gaofeng, Zhong, Peng, Wang, Guangji, Lei, ChangCheng, Tian, Guoping, Chen, Jingsong, Wu, Jianfeng, Shen, Caijie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318477/ https://www.ncbi.nlm.nih.gov/pubmed/34041859 http://dx.doi.org/10.1002/ehf2.13447

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