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Liver Transplant in a Polymerase Chain Reaction–Positive COVID-19 Recipient: A Case Report

The severe acute respiratory syndrome coronavirus 2 coronavirus disease 2019 (COVID-19) global pandemic has ushered in an era of hesitation in performing transplants in affected patients. This stems from the paucity of data regarding the testing modalities, long-term implications, and uncertain prog...

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Detalles Bibliográficos
Autores principales: Okubo, Keita, Iqbal, Sara, Lizaola-Mayo, Blanca, Aqel, Bashar, Graf, Erin H., Banacloche, Juan C. Gea, Singer, Andrew L., Harbell, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318687/
https://www.ncbi.nlm.nih.gov/pubmed/34446305
http://dx.doi.org/10.1016/j.transproceed.2021.07.045
Descripción
Sumario:The severe acute respiratory syndrome coronavirus 2 coronavirus disease 2019 (COVID-19) global pandemic has ushered in an era of hesitation in performing transplants in affected patients. This stems from the paucity of data regarding the testing modalities, long-term implications, and uncertain prognosis in this group of patients. Current guidance from the Centers for Disease Control recommends assessing symptoms rather than polymerase chain reaction (PCR) positivity. In light of these recommendations, we describe a case of an orthotopic liver transplant in a patient infected with COVID-19 with persistent PCR positivity for 40 days before retransplant. The patient's perioperative and postoperative course was uncomplicated. Our experience leads us to advocate for liver transplants in patients who are PCR positive for COVID-19 after careful individualized and multidisciplinary evaluation regarding their liver disease and COVID-19 symptomatology.