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Liver Transplant in a Polymerase Chain Reaction–Positive COVID-19 Recipient: A Case Report

The severe acute respiratory syndrome coronavirus 2 coronavirus disease 2019 (COVID-19) global pandemic has ushered in an era of hesitation in performing transplants in affected patients. This stems from the paucity of data regarding the testing modalities, long-term implications, and uncertain prog...

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Autores principales: Okubo, Keita, Iqbal, Sara, Lizaola-Mayo, Blanca, Aqel, Bashar, Graf, Erin H., Banacloche, Juan C. Gea, Singer, Andrew L., Harbell, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318687/
https://www.ncbi.nlm.nih.gov/pubmed/34446305
http://dx.doi.org/10.1016/j.transproceed.2021.07.045
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author Okubo, Keita
Iqbal, Sara
Lizaola-Mayo, Blanca
Aqel, Bashar
Graf, Erin H.
Banacloche, Juan C. Gea
Singer, Andrew L.
Harbell, Jack W.
author_facet Okubo, Keita
Iqbal, Sara
Lizaola-Mayo, Blanca
Aqel, Bashar
Graf, Erin H.
Banacloche, Juan C. Gea
Singer, Andrew L.
Harbell, Jack W.
author_sort Okubo, Keita
collection PubMed
description The severe acute respiratory syndrome coronavirus 2 coronavirus disease 2019 (COVID-19) global pandemic has ushered in an era of hesitation in performing transplants in affected patients. This stems from the paucity of data regarding the testing modalities, long-term implications, and uncertain prognosis in this group of patients. Current guidance from the Centers for Disease Control recommends assessing symptoms rather than polymerase chain reaction (PCR) positivity. In light of these recommendations, we describe a case of an orthotopic liver transplant in a patient infected with COVID-19 with persistent PCR positivity for 40 days before retransplant. The patient's perioperative and postoperative course was uncomplicated. Our experience leads us to advocate for liver transplants in patients who are PCR positive for COVID-19 after careful individualized and multidisciplinary evaluation regarding their liver disease and COVID-19 symptomatology.
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spelling pubmed-83186872021-07-29 Liver Transplant in a Polymerase Chain Reaction–Positive COVID-19 Recipient: A Case Report Okubo, Keita Iqbal, Sara Lizaola-Mayo, Blanca Aqel, Bashar Graf, Erin H. Banacloche, Juan C. Gea Singer, Andrew L. Harbell, Jack W. Transplant Proc Article The severe acute respiratory syndrome coronavirus 2 coronavirus disease 2019 (COVID-19) global pandemic has ushered in an era of hesitation in performing transplants in affected patients. This stems from the paucity of data regarding the testing modalities, long-term implications, and uncertain prognosis in this group of patients. Current guidance from the Centers for Disease Control recommends assessing symptoms rather than polymerase chain reaction (PCR) positivity. In light of these recommendations, we describe a case of an orthotopic liver transplant in a patient infected with COVID-19 with persistent PCR positivity for 40 days before retransplant. The patient's perioperative and postoperative course was uncomplicated. Our experience leads us to advocate for liver transplants in patients who are PCR positive for COVID-19 after careful individualized and multidisciplinary evaluation regarding their liver disease and COVID-19 symptomatology. Elsevier Inc. 2021-10 2021-07-29 /pmc/articles/PMC8318687/ /pubmed/34446305 http://dx.doi.org/10.1016/j.transproceed.2021.07.045 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Okubo, Keita
Iqbal, Sara
Lizaola-Mayo, Blanca
Aqel, Bashar
Graf, Erin H.
Banacloche, Juan C. Gea
Singer, Andrew L.
Harbell, Jack W.
Liver Transplant in a Polymerase Chain Reaction–Positive COVID-19 Recipient: A Case Report
title Liver Transplant in a Polymerase Chain Reaction–Positive COVID-19 Recipient: A Case Report
title_full Liver Transplant in a Polymerase Chain Reaction–Positive COVID-19 Recipient: A Case Report
title_fullStr Liver Transplant in a Polymerase Chain Reaction–Positive COVID-19 Recipient: A Case Report
title_full_unstemmed Liver Transplant in a Polymerase Chain Reaction–Positive COVID-19 Recipient: A Case Report
title_short Liver Transplant in a Polymerase Chain Reaction–Positive COVID-19 Recipient: A Case Report
title_sort liver transplant in a polymerase chain reaction–positive covid-19 recipient: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318687/
https://www.ncbi.nlm.nih.gov/pubmed/34446305
http://dx.doi.org/10.1016/j.transproceed.2021.07.045
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