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All-Trans Retinoic Acid Enhances Chemosensitivity to 5-FU by Targeting miR-378c/E2F7 Axis in Colorectal Cancer

Colorectal carcinoma (CRC), a life-threatening malignancy, has been found to present resistance to 5-fluorouracil (5-FU) and cause a poor prognosis for patients. Previous studies have proved that all-trans retinoic acid (ATRA) could inhibit the development of CRC cells. In addition, miR-378c was dis...

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Detalles Bibliográficos
Autores principales: Li, Ji, Xiang, Qing, Wang, Mei, Zhang, Hongchang, Liang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318767/
https://www.ncbi.nlm.nih.gov/pubmed/34335757
http://dx.doi.org/10.1155/2021/5338934