Cargando…
All-Trans Retinoic Acid Enhances Chemosensitivity to 5-FU by Targeting miR-378c/E2F7 Axis in Colorectal Cancer
Colorectal carcinoma (CRC), a life-threatening malignancy, has been found to present resistance to 5-fluorouracil (5-FU) and cause a poor prognosis for patients. Previous studies have proved that all-trans retinoic acid (ATRA) could inhibit the development of CRC cells. In addition, miR-378c was dis...
Autores principales: | Li, Ji, Xiang, Qing, Wang, Mei, Zhang, Hongchang, Liang, Rong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318767/ https://www.ncbi.nlm.nih.gov/pubmed/34335757 http://dx.doi.org/10.1155/2021/5338934 |
Ejemplares similares
-
miR-378a-3p regulates glioma cell chemosensitivity to cisplatin through IGF1R
por: Wang, Yunjiang, et al.
Publicado: (2021) -
Knockout of SIRT4 decreases chemosensitivity to 5-FU in colorectal cancer cells
por: Zhu, Yuanyuan, et al.
Publicado: (2018) -
miR-329 regulates the sensitivity of 5-FU in chemotherapy of colorectal cancer by targeting E2F1
por: Yin, Jie, et al.
Publicado: (2018) -
Depicting the Implication of miR-378a in Cancers
por: Qin, Yuelan, et al.
Publicado: (2022) -
miR-196b, miR-378a and miR-486 are predictive biomarkers for the efficacy of vaccine treatment in colorectal cancer
por: Shindo, Yoshitaro, et al.
Publicado: (2017)