Voltammetric determination of uric acid using multiwall carbon nanotubes coated-poly(4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode

In this study, an electrochemical sensor based multiwalled carbon nanotubes (MWCNTs)-poly (4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode (MWCNTs/poly (AHNSA)/GCE) was developed for the determination of uric acid (UA). The composite electrode was prepared first by elec...

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Autores principales: Tefera, Molla, Tessema, Merid, Admassie, Shimelis, Wubet, Walelign
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318863/
https://www.ncbi.nlm.nih.gov/pubmed/34337185
http://dx.doi.org/10.1016/j.heliyon.2021.e07575
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author Tefera, Molla
Tessema, Merid
Admassie, Shimelis
Wubet, Walelign
author_facet Tefera, Molla
Tessema, Merid
Admassie, Shimelis
Wubet, Walelign
author_sort Tefera, Molla
collection PubMed
description In this study, an electrochemical sensor based multiwalled carbon nanotubes (MWCNTs)-poly (4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode (MWCNTs/poly (AHNSA)/GCE) was developed for the determination of uric acid (UA). The composite electrode was prepared first by electropolymerization of the monomer (AHNSA) on GCE using cyclic voltammetry within the potential range of −0.8 V to +2.0 V vs Ag/AgCl for 15 cycles followed by drop coating of MWCNTs solution on the surface of poly (AHNSA)/GCE. Under optimal conditions, MWCNTs/poly (AHNSA)/GCE showed a linear current response with UA concentrations in the range of 1 × 10(−6) to 1 × 10(−4) M with R(2) = 0.9972. The sensor exhibited low detection limit with a value of 0.024 μM. The sensors have been applied to successfully quantify UA in urine samples.
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spelling pubmed-83188632021-07-31 Voltammetric determination of uric acid using multiwall carbon nanotubes coated-poly(4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode Tefera, Molla Tessema, Merid Admassie, Shimelis Wubet, Walelign Heliyon Research Article In this study, an electrochemical sensor based multiwalled carbon nanotubes (MWCNTs)-poly (4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode (MWCNTs/poly (AHNSA)/GCE) was developed for the determination of uric acid (UA). The composite electrode was prepared first by electropolymerization of the monomer (AHNSA) on GCE using cyclic voltammetry within the potential range of −0.8 V to +2.0 V vs Ag/AgCl for 15 cycles followed by drop coating of MWCNTs solution on the surface of poly (AHNSA)/GCE. Under optimal conditions, MWCNTs/poly (AHNSA)/GCE showed a linear current response with UA concentrations in the range of 1 × 10(−6) to 1 × 10(−4) M with R(2) = 0.9972. The sensor exhibited low detection limit with a value of 0.024 μM. The sensors have been applied to successfully quantify UA in urine samples. Elsevier 2021-07-15 /pmc/articles/PMC8318863/ /pubmed/34337185 http://dx.doi.org/10.1016/j.heliyon.2021.e07575 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Tefera, Molla
Tessema, Merid
Admassie, Shimelis
Wubet, Walelign
Voltammetric determination of uric acid using multiwall carbon nanotubes coated-poly(4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode
title Voltammetric determination of uric acid using multiwall carbon nanotubes coated-poly(4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode
title_full Voltammetric determination of uric acid using multiwall carbon nanotubes coated-poly(4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode
title_fullStr Voltammetric determination of uric acid using multiwall carbon nanotubes coated-poly(4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode
title_full_unstemmed Voltammetric determination of uric acid using multiwall carbon nanotubes coated-poly(4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode
title_short Voltammetric determination of uric acid using multiwall carbon nanotubes coated-poly(4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode
title_sort voltammetric determination of uric acid using multiwall carbon nanotubes coated-poly(4-amino-3-hydroxy naphthalene sulfonic acid) modified glassy carbon electrode
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318863/
https://www.ncbi.nlm.nih.gov/pubmed/34337185
http://dx.doi.org/10.1016/j.heliyon.2021.e07575
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