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Induction of antigen-specific Treg cells in treating autoimmune uveitis via bystander suppressive pathways without compromising anti-tumor immunity
BACKGROUND: Induction of autoantigen-specific Treg cells that suppress tissue-specific autoimmunity without compromising beneficial immune responses is the holy-grail for immunotherapy to autoimmune diseases. METHODS: In a model of experimental autoimmune uveitis (EAU) that mimics human uveitis, ocu...
Autores principales: | Chen, Zilin, Zhang, Tian, Kam, Hio Tong, Qiao, Dijie, Jin, Wenwen, Zhong, Yajie, Zhou, Minyi, Zhou, Hongyan, Chong, Wai Po, Chen, Wanjun, Chen, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318874/ https://www.ncbi.nlm.nih.gov/pubmed/34280776 http://dx.doi.org/10.1016/j.ebiom.2021.103496 |
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