SIRT7: an influence factor in healthy aging and the development of age-dependent myeloid stem-cell disorders

Molecular alterations within the hematopoietic system influence cellular longevity and development of age-related myeloid stem-cell disorders like acute myeloid leukemia (AML) and chronic myeloid leukemia (CML). A reduced SIRT7-expression in aged murine hematopoietic stem cells (HSC) resulted in red...

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Detalles Bibliográficos
Autores principales: Kaiser, Alexander, Schmidt, Martin, Huber, Otmar, Frietsch, Jochen J., Scholl, Sebastian, Heidel, Florian H., Hochhaus, Andreas, Müller, Jörg P., Ernst, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318878/
https://www.ncbi.nlm.nih.gov/pubmed/32214204
http://dx.doi.org/10.1038/s41375-020-0803-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318878/
https://www.ncbi.nlm.nih.gov/pubmed/32214204
http://dx.doi.org/10.1038/s41375-020-0803-3

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