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The role of PLCγ2 in immunological disorders, cancer, and neurodegeneration

Phosphatidylinositol-specific phospholipase Cγ2 (PLCγ2) is a critical signaling molecule activated downstream from a variety of cell surface receptors that contain an intracellular immunoreceptor tyrosine-based activation motif. These receptors recruit kinases such as Syk, BTK, and BLNK to phosphory...

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Detalles Bibliográficos
Autores principales:	Jackson, Jacob T., Mulazzani, Elisabeth, Nutt, Stephen L., Masters, Seth L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	JBC Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318911/ https://www.ncbi.nlm.nih.gov/pubmed/34157287 http://dx.doi.org/10.1016/j.jbc.2021.100905

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