Sensitive determination of gentamicin in plasma using ion-exchange solid-phase extraction followed by UHPLC-MS/MS analysis

BACKGROUND: Therapeutic drug monitoring (TDM) of gentamicin sulfate (GEN) is usually recommended, particularly in critical patients. Only a few reports had described the determination of GEN in plasma or plasma using LC-MS/MS. OBJECTIVE: This study aimed to develop and validate a sensitive ultra-hig...

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Detalles Bibliográficos
Autores principales: Anibaletto dos Santos, Ana Laura, Cezimbra da Silva, Anne Caroline, de Lima Feltraco Lizot, Lilian, Schneider, Anelise, Hahn, Roberta Zilles, Meireles, Yasmin Fazenda, Pagnussat, Lidiane Riva, Nonnenmacher, Julia Livia, Hahn, Siomara Regina, Linden, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318924/
https://www.ncbi.nlm.nih.gov/pubmed/34337126
http://dx.doi.org/10.1016/j.plabm.2021.e00246

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