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Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy
Portal hypertension, defined as increased pressure in the portal vein, develops as a consequence of increased intrahepatic vascular resistance due to the dysregulation of liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs), frequently arising from chronic liver diseases. Ext...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318926/ https://www.ncbi.nlm.nih.gov/pubmed/34337369 http://dx.doi.org/10.1016/j.jhepr.2021.100316 |