Precision Neoantigen Discovery Using Large-scale Immunopeptidomes and Composite Modeling of MHC Peptide Presentation

Major histocompatibility complex (MHC)-bound peptides that originate from tumor-specific genetic alterations, known as neoantigens, are an important class of anticancer therapeutic targets. Accurately predicting peptide presentation by MHC complexes is a key aspect of discovering therapeutically rel...

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Detalles Bibliográficos
Autores principales: Pyke, Rachel Marty, Mellacheruvu, Dattatreya, Dea, Steven, Abbott, Charles W., Zhang, Simo V., Phillips, Nick A., Harris, Jason, Bartha, Gabor, Desai, Sejal, McClory, Rena, West, John, Snyder, Michael P., Chen, Richard, Boyle, Sean Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Technological Innovation and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318994/
https://www.ncbi.nlm.nih.gov/pubmed/34126241
http://dx.doi.org/10.1016/j.mcpro.2021.100111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318994/
https://www.ncbi.nlm.nih.gov/pubmed/34126241
http://dx.doi.org/10.1016/j.mcpro.2021.100111

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