Impact of Amerind ancestry and FADS genetic variation on omega-3 deficiency and cardiometabolic traits in Hispanic populations

Long chain polyunsaturated fatty acids (LC-PUFAs) have critical signaling roles that regulate dyslipidemia and inflammation. Genetic variation in the FADS gene cluster accounts for a large portion of interindividual differences in circulating and tissue levels of LC-PUFAs, with the genotypes most st...

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Detalles Bibliográficos
Autores principales: Yang, Chaojie, Hallmark, Brian, Chai, Jin Choul, O’Connor, Timothy D., Reynolds, Lindsay M., Wood, Alexis C., Seeds, Michael, Chen, Yii-Der Ida, Steffen, Lyn M., Tsai, Michael Y., Kaplan, Robert C., Daviglus, Martha L., Mandarino, Lawrence J., Fretts, Amanda M., Lemaitre, Rozenn N., Coletta, Dawn K., Blomquist, Sarah A., Johnstone, Laurel M., Tontsch, Chandra, Qi, Qibin, Ruczinski, Ingo, Rich, Stephen S., Mathias, Rasika A., Chilton, Floyd H., Manichaikul, Ani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319323/
https://www.ncbi.nlm.nih.gov/pubmed/34321601
http://dx.doi.org/10.1038/s42003-021-02431-4

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