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Extrarenal expression of α-klotho, the kidney related longevity gene, in Heterocephalus glaber, the long living Naked Mole Rat

The Naked Mole Rat (NMR), Heterocephalus glaber, provides an interesting model for studying biomarkers of longevity due to its long lifespan of more than 30 years, almost ten times longer than that of mice and rats. α-Klotho (klotho) is an aging-suppressor gene, and overexpression of klotho is assoc...

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Detalles Bibliográficos
Autores principales: Morevati, M., Mace, M. L., Egstrand, S., Nordholm, A., Doganli, C., Strand, J., Rukov, J. L., Torsetnes, S. B., Gorbunova, V., Olgaard, K., Lewin, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319335/
https://www.ncbi.nlm.nih.gov/pubmed/34321565
http://dx.doi.org/10.1038/s41598-021-94972-1