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HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue
OBJECTIVE: Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial dysfunction with a decreased expression of the mitochondrial chaperone HSP60. The aim of this investigation was to determine the e...
Autores principales: | Hauffe, Robert, Rath, Michaela, Schell, Mareike, Ritter, Katrin, Kappert, Kai, Deubel, Stefanie, Ott, Christiane, Jähnert, Markus, Jonas, Wenke, Schürmann, Annette, Kleinridders, André |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319365/ https://www.ncbi.nlm.nih.gov/pubmed/34153520 http://dx.doi.org/10.1016/j.molmet.2021.101276 |
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