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Positron emission tomography imaging with (89)Zr-labeled anti-CD8 cys-diabody reveals CD8(+) cell infiltration during oncolytic virus therapy in a glioma murine model

Determination of treatment response to immunotherapy in glioblastoma multiforme (GBM) is a process which can take months. Detection of CD8(+) T cell recruitment to the tumor with a noninvasive imaging modality such as positron emission tomography (PET) may allow for tumor characterization and early...

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Detalles Bibliográficos
Autores principales: Kasten, Benjamin B., Houson, Hailey A., Coleman, Jennifer M., Leavenworth, Jianmei W., Markert, James M., Wu, Anna M., Salazar, Felix, Tavaré, Richard, Massicano, Adriana V. F., Gillespie, G. Yancey, Lapi, Suzanne E., Warram, Jason M., Sorace, Anna G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319402/
https://www.ncbi.nlm.nih.gov/pubmed/34321569
http://dx.doi.org/10.1038/s41598-021-94887-x