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Atrial Fibrillation and Cancer

Cancer patients have a higher risk of atrial fibrillation (AF) than general population, the pathophysiology mechanisms involves the pro inflammatory status of immune system in these patients and the exacerbated inflammatory response to cancer treatment and surgeries. Adequate management and prophyla...

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Autores principales: Hajjar, Ludhmila Abrahao, Fonseca, Silvia Moulin Ribeiro, Machado, Theuran Inahja Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319502/
https://www.ncbi.nlm.nih.gov/pubmed/34336939
http://dx.doi.org/10.3389/fcvm.2021.590768
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author Hajjar, Ludhmila Abrahao
Fonseca, Silvia Moulin Ribeiro
Machado, Theuran Inahja Vicente
author_facet Hajjar, Ludhmila Abrahao
Fonseca, Silvia Moulin Ribeiro
Machado, Theuran Inahja Vicente
author_sort Hajjar, Ludhmila Abrahao
collection PubMed
description Cancer patients have a higher risk of atrial fibrillation (AF) than general population, the pathophysiology mechanisms involves the pro inflammatory status of immune system in these patients and the exacerbated inflammatory response to cancer treatment and surgeries. Adequate management and prophylaxis for its occurrence are important and reduce morbidity and mortality in this population. There is a challenge in AF related to cancer to predict thromboembolic and bleeding risk in these patients, once standard stroke and hemorrhagic prediction scores are not validated for them. It is used CHA2DS2-VASc and HAS-BLED scores, the same as used in general population. In this review, we demonstrate correlated mechanisms to occurrence AF in cancer patients as well as therapeutic challenges in this population.
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spelling pubmed-83195022021-07-30 Atrial Fibrillation and Cancer Hajjar, Ludhmila Abrahao Fonseca, Silvia Moulin Ribeiro Machado, Theuran Inahja Vicente Front Cardiovasc Med Cardiovascular Medicine Cancer patients have a higher risk of atrial fibrillation (AF) than general population, the pathophysiology mechanisms involves the pro inflammatory status of immune system in these patients and the exacerbated inflammatory response to cancer treatment and surgeries. Adequate management and prophylaxis for its occurrence are important and reduce morbidity and mortality in this population. There is a challenge in AF related to cancer to predict thromboembolic and bleeding risk in these patients, once standard stroke and hemorrhagic prediction scores are not validated for them. It is used CHA2DS2-VASc and HAS-BLED scores, the same as used in general population. In this review, we demonstrate correlated mechanisms to occurrence AF in cancer patients as well as therapeutic challenges in this population. Frontiers Media S.A. 2021-07-15 /pmc/articles/PMC8319502/ /pubmed/34336939 http://dx.doi.org/10.3389/fcvm.2021.590768 Text en Copyright © 2021 Hajjar, Fonseca and Machado. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Hajjar, Ludhmila Abrahao
Fonseca, Silvia Moulin Ribeiro
Machado, Theuran Inahja Vicente
Atrial Fibrillation and Cancer
title Atrial Fibrillation and Cancer
title_full Atrial Fibrillation and Cancer
title_fullStr Atrial Fibrillation and Cancer
title_full_unstemmed Atrial Fibrillation and Cancer
title_short Atrial Fibrillation and Cancer
title_sort atrial fibrillation and cancer
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319502/
https://www.ncbi.nlm.nih.gov/pubmed/34336939
http://dx.doi.org/10.3389/fcvm.2021.590768
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