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Atrial Fibrillation and Cancer
Cancer patients have a higher risk of atrial fibrillation (AF) than general population, the pathophysiology mechanisms involves the pro inflammatory status of immune system in these patients and the exacerbated inflammatory response to cancer treatment and surgeries. Adequate management and prophyla...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319502/ https://www.ncbi.nlm.nih.gov/pubmed/34336939 http://dx.doi.org/10.3389/fcvm.2021.590768 |
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author | Hajjar, Ludhmila Abrahao Fonseca, Silvia Moulin Ribeiro Machado, Theuran Inahja Vicente |
author_facet | Hajjar, Ludhmila Abrahao Fonseca, Silvia Moulin Ribeiro Machado, Theuran Inahja Vicente |
author_sort | Hajjar, Ludhmila Abrahao |
collection | PubMed |
description | Cancer patients have a higher risk of atrial fibrillation (AF) than general population, the pathophysiology mechanisms involves the pro inflammatory status of immune system in these patients and the exacerbated inflammatory response to cancer treatment and surgeries. Adequate management and prophylaxis for its occurrence are important and reduce morbidity and mortality in this population. There is a challenge in AF related to cancer to predict thromboembolic and bleeding risk in these patients, once standard stroke and hemorrhagic prediction scores are not validated for them. It is used CHA2DS2-VASc and HAS-BLED scores, the same as used in general population. In this review, we demonstrate correlated mechanisms to occurrence AF in cancer patients as well as therapeutic challenges in this population. |
format | Online Article Text |
id | pubmed-8319502 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83195022021-07-30 Atrial Fibrillation and Cancer Hajjar, Ludhmila Abrahao Fonseca, Silvia Moulin Ribeiro Machado, Theuran Inahja Vicente Front Cardiovasc Med Cardiovascular Medicine Cancer patients have a higher risk of atrial fibrillation (AF) than general population, the pathophysiology mechanisms involves the pro inflammatory status of immune system in these patients and the exacerbated inflammatory response to cancer treatment and surgeries. Adequate management and prophylaxis for its occurrence are important and reduce morbidity and mortality in this population. There is a challenge in AF related to cancer to predict thromboembolic and bleeding risk in these patients, once standard stroke and hemorrhagic prediction scores are not validated for them. It is used CHA2DS2-VASc and HAS-BLED scores, the same as used in general population. In this review, we demonstrate correlated mechanisms to occurrence AF in cancer patients as well as therapeutic challenges in this population. Frontiers Media S.A. 2021-07-15 /pmc/articles/PMC8319502/ /pubmed/34336939 http://dx.doi.org/10.3389/fcvm.2021.590768 Text en Copyright © 2021 Hajjar, Fonseca and Machado. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cardiovascular Medicine Hajjar, Ludhmila Abrahao Fonseca, Silvia Moulin Ribeiro Machado, Theuran Inahja Vicente Atrial Fibrillation and Cancer |
title | Atrial Fibrillation and Cancer |
title_full | Atrial Fibrillation and Cancer |
title_fullStr | Atrial Fibrillation and Cancer |
title_full_unstemmed | Atrial Fibrillation and Cancer |
title_short | Atrial Fibrillation and Cancer |
title_sort | atrial fibrillation and cancer |
topic | Cardiovascular Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319502/ https://www.ncbi.nlm.nih.gov/pubmed/34336939 http://dx.doi.org/10.3389/fcvm.2021.590768 |
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