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Cryo-EM reveals conformational flexibility in apo DNA polymerase ζ

The translesion synthesis (TLS) DNA polymerases Rev1 and Polζ function together in DNA lesion bypass during DNA replication, acting as nucleotide inserter and extender polymerases, respectively. While the structural characterization of the Saccharomyces cerevisiae Polζ in its DNA-bound state has ill...

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Detalles Bibliográficos
Autores principales:	Du Truong, Chloe, Craig, Theodore A., Cui, Gaofeng, Botuyan, Maria Victoria, Serkasevich, Rachel A., Chan, Ka-Yi, Mer, Georges, Chiu, Po-Lin, Kumar, Rajiv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319531/ https://www.ncbi.nlm.nih.gov/pubmed/34174285 http://dx.doi.org/10.1016/j.jbc.2021.100912

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