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Radio-laboratory findings in COVID-19 anosmia patients: a single-center experience

BACKGROUND: There is solid evidence that olfactory dysfunction (OD) can present in COVID-19 patients. Anosmia can be the only presentation or can be accompanied by other symptoms of COVID-19. Multiple cross-sectional studies have demonstrated that the incidence rate of olfactory dysfunction is high...

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Autores principales: Algarf, Tareq Muhammad, Youssef, Mahmoud Atef, Elshazly, Mostafa, Ismail, Mohamed Said, Hasswa, Mohamed Kamal, Mousa, Mohamed Shaaban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319694/
http://dx.doi.org/10.1186/s43163-021-00133-6
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author Algarf, Tareq Muhammad
Youssef, Mahmoud Atef
Elshazly, Mostafa
Ismail, Mohamed Said
Hasswa, Mohamed Kamal
Mousa, Mohamed Shaaban
author_facet Algarf, Tareq Muhammad
Youssef, Mahmoud Atef
Elshazly, Mostafa
Ismail, Mohamed Said
Hasswa, Mohamed Kamal
Mousa, Mohamed Shaaban
author_sort Algarf, Tareq Muhammad
collection PubMed
description BACKGROUND: There is solid evidence that olfactory dysfunction (OD) can present in COVID-19 patients. Anosmia can be the only presentation or can be accompanied by other symptoms of COVID-19. Multiple cross-sectional studies have demonstrated that the incidence rate of olfactory dysfunction is high in COVID-19 patients with good prognosis. The aim of our study is to investigate the presence of OD with the radiologic and laboratory findings among COVID-19 positive patients. RESULTS: There was statistical significance in clinical severity between anosmia and non-anosmia group (P value 0.000) denoting that anosmia sign mostly occur in mild COVID. Also, there was significance in D dimer between two groups (P value 0.044) denoting that D dimer could be a sign of clinical severity and it is usually not elevated in anosmia. All anosmia group had normal CT chest denoting that it is a mild form of COVID-19. CONCLUSIONS: Olfactory dysfunction (OD) is an imminent sign of COVID-19 patient, which can be presented as a sole symptom or with other symptoms. As anosmia could be the sole clinical presentation of COVID-19 patients without any other significant signs and so otolaryngologists should be aware of this presentation in COVID-19 diagnosis.
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spelling pubmed-83196942021-07-29 Radio-laboratory findings in COVID-19 anosmia patients: a single-center experience Algarf, Tareq Muhammad Youssef, Mahmoud Atef Elshazly, Mostafa Ismail, Mohamed Said Hasswa, Mohamed Kamal Mousa, Mohamed Shaaban Egypt J Otolaryngol Original Article BACKGROUND: There is solid evidence that olfactory dysfunction (OD) can present in COVID-19 patients. Anosmia can be the only presentation or can be accompanied by other symptoms of COVID-19. Multiple cross-sectional studies have demonstrated that the incidence rate of olfactory dysfunction is high in COVID-19 patients with good prognosis. The aim of our study is to investigate the presence of OD with the radiologic and laboratory findings among COVID-19 positive patients. RESULTS: There was statistical significance in clinical severity between anosmia and non-anosmia group (P value 0.000) denoting that anosmia sign mostly occur in mild COVID. Also, there was significance in D dimer between two groups (P value 0.044) denoting that D dimer could be a sign of clinical severity and it is usually not elevated in anosmia. All anosmia group had normal CT chest denoting that it is a mild form of COVID-19. CONCLUSIONS: Olfactory dysfunction (OD) is an imminent sign of COVID-19 patient, which can be presented as a sole symptom or with other symptoms. As anosmia could be the sole clinical presentation of COVID-19 patients without any other significant signs and so otolaryngologists should be aware of this presentation in COVID-19 diagnosis. Springer Berlin Heidelberg 2021-07-29 2021 /pmc/articles/PMC8319694/ http://dx.doi.org/10.1186/s43163-021-00133-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Algarf, Tareq Muhammad
Youssef, Mahmoud Atef
Elshazly, Mostafa
Ismail, Mohamed Said
Hasswa, Mohamed Kamal
Mousa, Mohamed Shaaban
Radio-laboratory findings in COVID-19 anosmia patients: a single-center experience
title Radio-laboratory findings in COVID-19 anosmia patients: a single-center experience
title_full Radio-laboratory findings in COVID-19 anosmia patients: a single-center experience
title_fullStr Radio-laboratory findings in COVID-19 anosmia patients: a single-center experience
title_full_unstemmed Radio-laboratory findings in COVID-19 anosmia patients: a single-center experience
title_short Radio-laboratory findings in COVID-19 anosmia patients: a single-center experience
title_sort radio-laboratory findings in covid-19 anosmia patients: a single-center experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319694/
http://dx.doi.org/10.1186/s43163-021-00133-6
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