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Fusobacterium nucleatum CbpF Mediates Inhibition of T Cell Function Through CEACAM1 Activation

F. nucleatum is an anaerobic bacterium that is associated with several tumor entities and promotes tumorigenesis. Recent evidence suggests that F. nucleatum binds the inhibitory receptor carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) via the trimeric autotransporter adhesin CbpF. Howeve...

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Detalles Bibliográficos
Autores principales: Galaski, Johanna, Shhadeh, Amjad, Umaña, Ariana, Yoo, Christopher C., Arpinati, Ludovica, Isaacson, Batya, Berhani, Orit, Singer, Bernhard B., Slade, Daniel J., Bachrach, Gilad, Mandelboim, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319768/
https://www.ncbi.nlm.nih.gov/pubmed/34336716
http://dx.doi.org/10.3389/fcimb.2021.692544