Comprehensive Deep Mutational Scanning Reveals the Immune-Escaping Hotspots of SARS-CoV-2 Receptor-Binding Domain Targeting Neutralizing Antibodies

The rapid spread of SARS-CoV-2 has caused the COVID-19 pandemic, resulting in the collapse of medical care systems and economic depression worldwide. To combat COVID-19, neutralizing antibodies have been investigated and developed. However, the evolutions (mutations) of the receptor-binding domain (...

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Detalles Bibliográficos
Autores principales: Tsai, Keng-Chang, Lee, Yu-Ching, Tseng, Tien-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319916/
https://www.ncbi.nlm.nih.gov/pubmed/34335530
http://dx.doi.org/10.3389/fmicb.2021.698365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319916/
https://www.ncbi.nlm.nih.gov/pubmed/34335530
http://dx.doi.org/10.3389/fmicb.2021.698365

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