Cargando…

A Novel Small Molecule Neurotrophin-3 Analogue Promotes Inner Ear Neurite Outgrowth and Synaptogenesis In vitro

Sensorineural hearing loss is irreversible and is associated with the loss of spiral ganglion neurons (SGNs) and sensory hair cells within the inner ear. Improving spiral ganglion neuron (SGN) survival, neurite outgrowth, and synaptogenesis could lead to significant gains for hearing-impaired patien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kempfle, Judith S., Duro, Marlon V., Zhang, Andrea, Amador, Carolina D., Kuang, Richard, Lu, Ryan, Kashemirov, Boris A., Edge, Albert S., McKenna, Charles E., Jung, David H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8319950/ https://www.ncbi.nlm.nih.gov/pubmed/34335184 http://dx.doi.org/10.3389/fncel.2021.666706

Ejemplares similares

Matrix interactions modulate neurotrophin-mediated neurite outgrowth and pathfinding
por: Madl, Christopher M., et al.
Publicado: (2015)

Electrical Stimulation with a Conductive Polymer Promotes Neurite Outgrowth and Synaptogenesis in Primary Cortical Neurons in 3D
por: Zhang, Qingsheng, et al.
Publicado: (2018)

Nesca, a novel adapter, translocates to the nuclear envelope and regulates neurotrophin-induced neurite outgrowth
por: MacDonald, James I.S., et al.
Publicado: (2004)

PDZ-RhoGEF ubiquitination by Cullin3–KLHL20 controls neurotrophin-induced neurite outgrowth
por: Lin, Mei-Yao, et al.
Publicado: (2011)

Soluble β-amyloid Precursor Protein Alpha Binds to p75 Neurotrophin Receptor to Promote Neurite Outgrowth
por: Hasebe, Noriko, et al.
Publicado: (2013)

Neurotrophin Promotes Neurite Outgrowth by Inhibiting Rif GTPase Activation Downstream of MAPKs and PI3K Signaling
por: Tian, Xiaoxia, et al.
Publicado: (2017)

The lncRNA MALAT1/miR-30/Spastin Axis Regulates Hippocampal Neurite Outgrowth
por: Jiang, Tao, et al.
Publicado: (2020)

Hepatocyte Growth Factor-Preconditioned Neural Progenitor Cells Attenuate Astrocyte Reactivity and Promote Neurite Outgrowth
por: Hong, James, et al.
Publicado: (2021)

Nanocarriers for Inner Ear Disease Therapy
por: Xu, Xiaoxiang, et al.
Publicado: (2021)

Improving Control of Gene Therapy-Based Neurotrophin Delivery for Inner Ear Applications
por: St. Peter, Madeleine, et al.
Publicado: (2022)

Organotypic Culture of Neonatal Murine Inner Ear Explants
por: Ogier, Jacqueline M., et al.
Publicado: (2019)

Local Delivery of Therapeutics to the Inner Ear: The State of the Science
por: Anderson, Caroline R., et al.
Publicado: (2019)

Navigating Hereditary Hearing Loss: Pathology of the Inner Ear
por: Nicolson, Teresa
Publicado: (2021)

Neurite Outgrowth Inhibitors in Gliotic Tissue
por: Nieto-Sampedro, M., et al.
Publicado: (1992)

The impact of resource competition on neurite outgrowth
por: Hjorth, Johannes JJ, et al.
Publicado: (2011)

Proteoglycans: Road Signs for Neurite Outgrowth
por: Beller, Justin A., et al.
Publicado: (2014)

An Integrated Cytoskeletal Model of Neurite Outgrowth
por: Miller, Kyle E., et al.
Publicado: (2018)

Lactate transport facilitates neurite outgrowth
por: Chen, Kun, et al.
Publicado: (2018)

Ultrasonic control of neurite outgrowth direction
por: Maruyama, Haruki, et al.
Publicado: (2021)

Mycobacterium smegmatis Induces Neurite Outgrowth and Differentiation in an Autophagy-Independent Manner in PC12 and C17.2 Cells
por: Feng, Xinwei, et al.
Publicado: (2018)

Endolymphatic Potential Measured From Developing and Adult Mouse Inner Ear
por: Li, Yi, et al.
Publicado: (2020)

The Effects of Hematopoietic Growth Factors on Neurite Outgrowth
por: Su, Ye, et al.
Publicado: (2013)

Inducing Neurite Outgrowth by Mechanical Cell Stretch
por: Higgins, Suzanne, et al.
Publicado: (2013)

Releasing Nrf2 to promote neurite outgrowth
por: Yang, Chuanbin, et al.
Publicado: (2015)

The Role of Bioactive Compounds on the Promotion of Neurite Outgrowth
por: More, Sandeep Vasant, et al.
Publicado: (2012)

Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth
por: Hisata, Shu, et al.
Publicado: (2007)

Suppression of p75 Neurotrophin Receptor Surface Expression with Intrabodies Influences Bcl-xL mRNA Expression and Neurite Outgrowth in PC12 Cells
por: Zhang, Congcong, et al.
Publicado: (2012)

Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells
por: Meng, Pan, et al.
Publicado: (2019)

Analysis of gene expression during neurite outgrowth and regeneration
por: Szpara, Moriah L, et al.
Publicado: (2007)

Neurite outgrowth in peripherin-depleted PC12 cells
Publicado: (1992)

Pea3 transcription factor promotes neurite outgrowth
por: Kandemir, Basak, et al.
Publicado: (2014)

Competitive Dynamics during Resource-Driven Neurite Outgrowth
por: Hjorth, J. J. Johannes, et al.
Publicado: (2014)

CRMP-5 interacts with actin to regulate neurite outgrowth
por: GONG, XIAOBING, et al.
Publicado: (2016)

Advanced Glycation Endproducts Interfere with Adhesion and Neurite Outgrowth
por: Bennmann, Dorit, et al.
Publicado: (2014)

Research advances on neurite outgrowth inhibitor B receptor
por: Zhang, Rui, et al.
Publicado: (2020)

Enhancement of Neurite Outgrowth by Warming Biomaterial Ultrasound Treatment
por: Chen, Jung-Chih, et al.
Publicado: (2020)

Neurite Outgrowth-Promoting Compounds from Cockscomb Hydrolysate
por: Koga, Takeru, et al.
Publicado: (2022)

Effects of MAP4K inhibition on neurite outgrowth
por: Lasham, Di Ja, et al.
Publicado: (2023)

Oligodendrocyte Precursor Cells Transplantation Improves Stroke Recovery via Oligodendrogenesis, Neurite Growth and Synaptogenesis
por: Li, Wanlu, et al.
Publicado: (2021)

Neurotrophins differentially stimulate the growth of cochlear neurites on collagen surfaces and in gels
por: Xie, Joanna, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_hr9lju4hu0vt649aj6egnibvps