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Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management

A growing body of evidence points to the frequent involvement of pulmonary microvessels in COVID-19 which was recognized first on CT, and subsequently demonstrated by clinical and pathological studies. Microvasculopathy occurring chiefly from endothelial and pericyte damage with resultant disruption...

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Detalles Bibliográficos
Autores principales: Parry, Arshed Hussain, Wani, Abdul Haseeb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320153/
https://www.ncbi.nlm.nih.gov/pubmed/34381939
http://dx.doi.org/10.1259/bjro.20210001
Descripción
Sumario:A growing body of evidence points to the frequent involvement of pulmonary microvessels in COVID-19 which was recognized first on CT, and subsequently demonstrated by clinical and pathological studies. Microvasculopathy occurring chiefly from endothelial and pericyte damage with resultant disruption of immune, thrombotic and renin–angiotensin–aldosterone balance leads to a constellation of clinical and biochemical derangements. Exploration of potential therapies directed at normalizing the vascular health can prove a major boon in the treatment of COVID-19.