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Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management

A growing body of evidence points to the frequent involvement of pulmonary microvessels in COVID-19 which was recognized first on CT, and subsequently demonstrated by clinical and pathological studies. Microvasculopathy occurring chiefly from endothelial and pericyte damage with resultant disruption...

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Detalles Bibliográficos
Autores principales: Parry, Arshed Hussain, Wani, Abdul Haseeb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320153/
https://www.ncbi.nlm.nih.gov/pubmed/34381939
http://dx.doi.org/10.1259/bjro.20210001
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author Parry, Arshed Hussain
Wani, Abdul Haseeb
author_facet Parry, Arshed Hussain
Wani, Abdul Haseeb
author_sort Parry, Arshed Hussain
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description A growing body of evidence points to the frequent involvement of pulmonary microvessels in COVID-19 which was recognized first on CT, and subsequently demonstrated by clinical and pathological studies. Microvasculopathy occurring chiefly from endothelial and pericyte damage with resultant disruption of immune, thrombotic and renin–angiotensin–aldosterone balance leads to a constellation of clinical and biochemical derangements. Exploration of potential therapies directed at normalizing the vascular health can prove a major boon in the treatment of COVID-19.
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spelling pubmed-83201532021-08-10 Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management Parry, Arshed Hussain Wani, Abdul Haseeb BJR Open Opinion A growing body of evidence points to the frequent involvement of pulmonary microvessels in COVID-19 which was recognized first on CT, and subsequently demonstrated by clinical and pathological studies. Microvasculopathy occurring chiefly from endothelial and pericyte damage with resultant disruption of immune, thrombotic and renin–angiotensin–aldosterone balance leads to a constellation of clinical and biochemical derangements. Exploration of potential therapies directed at normalizing the vascular health can prove a major boon in the treatment of COVID-19. The British Institute of Radiology. 2021-07-05 /pmc/articles/PMC8320153/ /pubmed/34381939 http://dx.doi.org/10.1259/bjro.20210001 Text en © 2021 The Authors. Published by the British Institute of Radiology https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Opinion
Parry, Arshed Hussain
Wani, Abdul Haseeb
Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management
title Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management
title_full Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management
title_fullStr Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management
title_full_unstemmed Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management
title_short Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management
title_sort novel pulmonary vascular imaging signs in covid-19: pathophysiology, significance and management
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320153/
https://www.ncbi.nlm.nih.gov/pubmed/34381939
http://dx.doi.org/10.1259/bjro.20210001
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