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Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management
A growing body of evidence points to the frequent involvement of pulmonary microvessels in COVID-19 which was recognized first on CT, and subsequently demonstrated by clinical and pathological studies. Microvasculopathy occurring chiefly from endothelial and pericyte damage with resultant disruption...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Institute of Radiology.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320153/ https://www.ncbi.nlm.nih.gov/pubmed/34381939 http://dx.doi.org/10.1259/bjro.20210001 |
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author | Parry, Arshed Hussain Wani, Abdul Haseeb |
author_facet | Parry, Arshed Hussain Wani, Abdul Haseeb |
author_sort | Parry, Arshed Hussain |
collection | PubMed |
description | A growing body of evidence points to the frequent involvement of pulmonary microvessels in COVID-19 which was recognized first on CT, and subsequently demonstrated by clinical and pathological studies. Microvasculopathy occurring chiefly from endothelial and pericyte damage with resultant disruption of immune, thrombotic and renin–angiotensin–aldosterone balance leads to a constellation of clinical and biochemical derangements. Exploration of potential therapies directed at normalizing the vascular health can prove a major boon in the treatment of COVID-19. |
format | Online Article Text |
id | pubmed-8320153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The British Institute of Radiology. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83201532021-08-10 Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management Parry, Arshed Hussain Wani, Abdul Haseeb BJR Open Opinion A growing body of evidence points to the frequent involvement of pulmonary microvessels in COVID-19 which was recognized first on CT, and subsequently demonstrated by clinical and pathological studies. Microvasculopathy occurring chiefly from endothelial and pericyte damage with resultant disruption of immune, thrombotic and renin–angiotensin–aldosterone balance leads to a constellation of clinical and biochemical derangements. Exploration of potential therapies directed at normalizing the vascular health can prove a major boon in the treatment of COVID-19. The British Institute of Radiology. 2021-07-05 /pmc/articles/PMC8320153/ /pubmed/34381939 http://dx.doi.org/10.1259/bjro.20210001 Text en © 2021 The Authors. Published by the British Institute of Radiology https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Opinion Parry, Arshed Hussain Wani, Abdul Haseeb Novel pulmonary vascular imaging signs in COVID-19: pathophysiology, significance and management |
title | Novel pulmonary vascular imaging signs in COVID-19: pathophysiology,
significance and management |
title_full | Novel pulmonary vascular imaging signs in COVID-19: pathophysiology,
significance and management |
title_fullStr | Novel pulmonary vascular imaging signs in COVID-19: pathophysiology,
significance and management |
title_full_unstemmed | Novel pulmonary vascular imaging signs in COVID-19: pathophysiology,
significance and management |
title_short | Novel pulmonary vascular imaging signs in COVID-19: pathophysiology,
significance and management |
title_sort | novel pulmonary vascular imaging signs in covid-19: pathophysiology,
significance and management |
topic | Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320153/ https://www.ncbi.nlm.nih.gov/pubmed/34381939 http://dx.doi.org/10.1259/bjro.20210001 |
work_keys_str_mv | AT parryarshedhussain novelpulmonaryvascularimagingsignsincovid19pathophysiologysignificanceandmanagement AT waniabdulhaseeb novelpulmonaryvascularimagingsignsincovid19pathophysiologysignificanceandmanagement |