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Sensitivity of cohesin–chromatin association to high-salt treatment corroborates non-topological mode of loop extrusion
Cohesin is a key organizer of chromatin folding in eukaryotic cells. The two main activities of this ring-shaped protein complex are the maintenance of sister chromatid cohesion and the establishment of long-range DNA–DNA interactions through the process of loop extrusion. Although the basic princip...
Autores principales: | Golov, Arkadiy K., Golova, Anastasia V., Gavrilov, Alexey A., Razin, Sergey V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320178/ https://www.ncbi.nlm.nih.gov/pubmed/34321070 http://dx.doi.org/10.1186/s13072-021-00411-w |
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