Choriocarcinoma brain metastasis in a patient in the third trimester: a case report

BACKGROUND: Metastatic choriocarcinoma in the third trimester of pregnancy is extremely rare. CASE PRESENTATION: A 25-year-old Chinese woman (gravida 3, para 0) who was 28 weeks pregnant was admitted for sudden convulsion, aconuresis, and unconsciousness. The decision was made to perform an emergenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Chunjuan, Ai, Ling, Li, Kai, Cao, Yunfei, Wu, Hanbing, Sun, Dandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320190/
https://www.ncbi.nlm.nih.gov/pubmed/34325722
http://dx.doi.org/10.1186/s13256-021-02808-3
_version_ 1783730601383165952
author Shen, Chunjuan
Ai, Ling
Li, Kai
Cao, Yunfei
Wu, Hanbing
Sun, Dandan
author_facet Shen, Chunjuan
Ai, Ling
Li, Kai
Cao, Yunfei
Wu, Hanbing
Sun, Dandan
author_sort Shen, Chunjuan
collection PubMed
description BACKGROUND: Metastatic choriocarcinoma in the third trimester of pregnancy is extremely rare. CASE PRESENTATION: A 25-year-old Chinese woman (gravida 3, para 0) who was 28 weeks pregnant was admitted for sudden convulsion, aconuresis, and unconsciousness. The decision was made to perform an emergency cesarean delivery and craniotomy, hematoma clearance, and decompression. Pathological examination confirmed choriocarcinoma with brain metastasis. The patient underwent chemotherapy with the etoposide, cisplatin (EP) and etoposide, methotrexate and dactinomycin alternating with cyclophosphamide and vincristine (EMACO) regimens. A satisfactory result was achieved. CONCLUSIONS: When encountering intracranial mass or bilateral pulmonary nodules in a pregnant woman, especially one in the third trimester, metastatic choriocarcinoma should be considered.
format Online
Article
Text
id pubmed-8320190
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-83201902021-07-30 Choriocarcinoma brain metastasis in a patient in the third trimester: a case report Shen, Chunjuan Ai, Ling Li, Kai Cao, Yunfei Wu, Hanbing Sun, Dandan J Med Case Rep Case Report BACKGROUND: Metastatic choriocarcinoma in the third trimester of pregnancy is extremely rare. CASE PRESENTATION: A 25-year-old Chinese woman (gravida 3, para 0) who was 28 weeks pregnant was admitted for sudden convulsion, aconuresis, and unconsciousness. The decision was made to perform an emergency cesarean delivery and craniotomy, hematoma clearance, and decompression. Pathological examination confirmed choriocarcinoma with brain metastasis. The patient underwent chemotherapy with the etoposide, cisplatin (EP) and etoposide, methotrexate and dactinomycin alternating with cyclophosphamide and vincristine (EMACO) regimens. A satisfactory result was achieved. CONCLUSIONS: When encountering intracranial mass or bilateral pulmonary nodules in a pregnant woman, especially one in the third trimester, metastatic choriocarcinoma should be considered. BioMed Central 2021-07-29 /pmc/articles/PMC8320190/ /pubmed/34325722 http://dx.doi.org/10.1186/s13256-021-02808-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Shen, Chunjuan
Ai, Ling
Li, Kai
Cao, Yunfei
Wu, Hanbing
Sun, Dandan
Choriocarcinoma brain metastasis in a patient in the third trimester: a case report
title Choriocarcinoma brain metastasis in a patient in the third trimester: a case report
title_full Choriocarcinoma brain metastasis in a patient in the third trimester: a case report
title_fullStr Choriocarcinoma brain metastasis in a patient in the third trimester: a case report
title_full_unstemmed Choriocarcinoma brain metastasis in a patient in the third trimester: a case report
title_short Choriocarcinoma brain metastasis in a patient in the third trimester: a case report
title_sort choriocarcinoma brain metastasis in a patient in the third trimester: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320190/
https://www.ncbi.nlm.nih.gov/pubmed/34325722
http://dx.doi.org/10.1186/s13256-021-02808-3
work_keys_str_mv AT shenchunjuan choriocarcinomabrainmetastasisinapatientinthethirdtrimesteracasereport
AT ailing choriocarcinomabrainmetastasisinapatientinthethirdtrimesteracasereport
AT likai choriocarcinomabrainmetastasisinapatientinthethirdtrimesteracasereport
AT caoyunfei choriocarcinomabrainmetastasisinapatientinthethirdtrimesteracasereport
AT wuhanbing choriocarcinomabrainmetastasisinapatientinthethirdtrimesteracasereport
AT sundandan choriocarcinomabrainmetastasisinapatientinthethirdtrimesteracasereport

Ejemplares similares