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Silent cold-sensing neurons contribute to cold allodynia in neuropathic pain

Patients with neuropathic pain often experience innocuous cooling as excruciating pain. The cell and molecular basis of this cold allodynia is little understood. We used in vivo calcium imaging of sensory ganglia to investigate how the activity of peripheral cold-sensing neurons was altered in three...

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Detalles Bibliográficos
Autores principales: MacDonald, Donald Iain, Luiz, Ana P, Iseppon, Federico, Millet, Queensta, Emery, Edward C, Wood, John N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320254/
https://www.ncbi.nlm.nih.gov/pubmed/33693512
http://dx.doi.org/10.1093/brain/awab086