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Ageing promotes pathological alpha-synuclein propagation and autonomic dysfunction in wild-type rats
Neuronal aggregates of misfolded alpha-synuclein protein are found in the brain and periphery of patients with Parkinson’s disease. Braak and colleagues have hypothesized that the initial formation of misfolded alpha-synuclein may start in the gut, and then spread to the brain via peripheral autonom...
Autores principales: | Van Den Berge, Nathalie, Ferreira, Nelson, Mikkelsen, Trine Werenberg, Alstrup, Aage Kristian Olsen, Tamgüney, Gültekin, Karlsson, Páll, Terkelsen, Astrid Juhl, Nyengaard, Jens Randel, Jensen, Poul Henning, Borghammer, Per |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320301/ https://www.ncbi.nlm.nih.gov/pubmed/33880502 http://dx.doi.org/10.1093/brain/awab061 |
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