Targeting Neoepitopes to Treat Solid Malignancies: Immunosurgery

Successful outcome of immune checkpoint blockade in patients with solid cancers is in part associated with a high tumor mutational burden (TMB) and the recognition of private neoantigens by T-cells. The quality and quantity of target recognition is determined by the repertoire of ‘neoepitope’-specif...

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Detalles Bibliográficos
Autores principales: de Sousa, Eric, Lérias, Joana R., Beltran, Antonio, Paraschoudi, Georgia, Condeço, Carolina, Kamiki, Jéssica, António, Patrícia Alexandra, Figueiredo, Nuno, Carvalho, Carlos, Castillo-Martin, Mireia, Wang, Zhe, Ligeiro, Dário, Rao, Martin, Maeurer, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320363/
https://www.ncbi.nlm.nih.gov/pubmed/34335558
http://dx.doi.org/10.3389/fimmu.2021.592031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320363/
https://www.ncbi.nlm.nih.gov/pubmed/34335558
http://dx.doi.org/10.3389/fimmu.2021.592031

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