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Targeting Neoepitopes to Treat Solid Malignancies: Immunosurgery
Successful outcome of immune checkpoint blockade in patients with solid cancers is in part associated with a high tumor mutational burden (TMB) and the recognition of private neoantigens by T-cells. The quality and quantity of target recognition is determined by the repertoire of ‘neoepitope’-specif...
Autores principales: | de Sousa, Eric, Lérias, Joana R., Beltran, Antonio, Paraschoudi, Georgia, Condeço, Carolina, Kamiki, Jéssica, António, Patrícia Alexandra, Figueiredo, Nuno, Carvalho, Carlos, Castillo-Martin, Mireia, Wang, Zhe, Ligeiro, Dário, Rao, Martin, Maeurer, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320363/ https://www.ncbi.nlm.nih.gov/pubmed/34335558 http://dx.doi.org/10.3389/fimmu.2021.592031 |
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