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Short- and long-term effects on reproductive parameters of female Wistar rats after exposure to rosuvastatin starting in pre-puberty
Statins are a class of drugs that act lowering lipid levels by inhibiting cholesterol biosynthesis. Additionally, statins can act by “pleiotropic effects”, related to the inhibition of synthesis of the other mevalonate pathway products. Rosuvastatin is a third-generation statin and has shown better...
Autores principales: | Barros, Jorge W.F., Tonon, Karolina S., Borges, Cibele S., Silva, Patrícia V., Lozano, Ana F.Q., Pacheco, Tainá L., Anselmo-Franci, Janete A., Kempinas, Wilma G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320644/ https://www.ncbi.nlm.nih.gov/pubmed/34345844 http://dx.doi.org/10.1016/j.crtox.2020.11.002 |
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