Paraneoplastic Hyperfibrinolysis: Detection of Occult Prostate Cancer with 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography

Hyperfibrinolysis caused by abnormal over-activation of the fibrinolytic system can be associated with occult cancer. We present an interesting case of a 48-year-old man with paraneoplastic hyperfibrinolysis, where (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography-computed tomography...

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Detalles Bibliográficos
Autor principal: Sharma, Punit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320818/
https://www.ncbi.nlm.nih.gov/pubmed/34385796
http://dx.doi.org/10.4103/ijnm.IJNM_195_20
Descripción
Sumario:Hyperfibrinolysis caused by abnormal over-activation of the fibrinolytic system can be associated with occult cancer. We present an interesting case of a 48-year-old man with paraneoplastic hyperfibrinolysis, where (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography-computed tomography (PET-CT) was able to detect occult prostate-specific antigen-negative metastatic prostate cancer as the underlying etiology. This shows that while (18)F-FDG PET-CT has overall poor sensitivity for prostate cancer, it can be useful in certain clinical situations.

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