Cargando…

Mechanism of Anti-Inflammatory and Antibacterial Effects of QingXiaoWuWei Decoction Based on Network Pharmacology, Molecular Docking and In Vitro Experiments

Background and Aim: QingXiaoWuWei Decoction (QXWWD) is a traditional Chinese medicine that is commonly used in clinical settings to treat inflammatory and bacterial diseases. However, there is still a lot to learn about its molecular mechanism. A network pharmacology approach was applied to investig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Qian, Li, Xue, Li, Jun, Hu, Yuxia, Liu, Jing, Wang, Fang, Zhang, Wei, Chang, Fuhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320847/ https://www.ncbi.nlm.nih.gov/pubmed/34335250 http://dx.doi.org/10.3389/fphar.2021.678685

Ejemplares similares

Wu-Tou Decoction in Rheumatoid Arthritis: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation
por: Guo, Qingqing, et al.
Publicado: (2017)

Network Pharmacology-Based Analysis of Xiao-Xu-Ming Decoction on the Treatment of Alzheimer’s Disease
por: Shen, Yanjia, et al.
Publicado: (2020)

Qing-Yi Decoction in the Treatment of Acute Pancreatitis: An Integrated Approach Based on Chemical Profile, Network Pharmacology, Molecular Docking and Experimental Evaluation
por: Wei, Tian-Fu, et al.
Publicado: (2021)

A Systems Pharmacology Approach for Identifying the Multiple Mechanisms of Action of the Wei Pi Xiao Decoction for the Treatment of Gastric Precancerous Lesions
por: Yang, Liangjun, et al.
Publicado: (2019)

Qing-Re-Xiao-Zheng-Yi-Qi formula relieves kidney damage and activates mitophagy in diabetic kidney disease
por: Wu, Qiaoru, et al.
Publicado: (2022)

A Comprehensive Review of the Main Lignan Components of Schisandra chinensis (North Wu Wei Zi) and Schisandra sphenanthera (South Wu Wei Zi) and the Lignan-Induced Drug-Drug Interactions Based on the Inhibition of Cytochrome P450 and P-Glycoprotein Activities
por: Zhang, Feng, et al.
Publicado: (2022)

Network Pharmacology and Experimental Validation to Explore the Mechanism of Qing-Jin-Hua-Tan-Decoction Against Acute Lung Injury
por: Xiao, Shunli, et al.
Publicado: (2022)

Chemical characterization and metabolic profiling of Xiao-Er-An-Shen Decoction by UPLC-QTOF/MS
por: Yang, Ruipei, et al.
Publicado: (2023)

Perturbed Lipidomic Profiles in Rats With Chronic Cerebral Ischemia Are Regulated by Xiao-Xu-Ming Decoction
por: Jia, Zhixin, et al.
Publicado: (2019)

Mechanism of Zhen Wu Decoction in the Treatment of Heart Failure Based on Network Pharmacology and Molecular Docking
por: Ma, Chen-Yu, et al.
Publicado: (2022)

Network pharmacology, molecular docking, and experimental validation to explore the potential mechanism of Long Mu Qing Xin mixture for the treatment of attention deficit hyperactivity disorder
por: Li, Xuejun, et al.
Publicado: (2023)

The potential mechanism of Longsheyangquan Decoction on the treatment of bladder cancer: Systemic network pharmacology and molecular docking
por: Cheng, Zhang, et al.
Publicado: (2022)

Network pharmacology and molecular docking to elucidate the mechanism of pulsatilla decoction in the treatment of colon cancer
por: Liu, Huan, et al.
Publicado: (2022)

Proteomic Analysis Provides Insights Into the Therapeutic Effect of GU-BEN-FANG-XIAO Decoction on a Persistent Asthmatic Mouse Model
por: Liu, Li-wei, et al.
Publicado: (2019)

Network pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of Huang–Qi–Gui–Zhi–Wu–Wu decoction against deep vein thrombosis
por: Fan, Wei, et al.
Publicado: (2023)

A randomized controlled trial study protocol for Xiao-Qing-Long decoction in the treatment of refractory asthma: Study protocol clinical trial (spirit compliant)
por: Yang, Hongjing, et al.
Publicado: (2020)

Exploring the mechanism of Suanzaoren decoction in treatment of insomnia based on network pharmacology and molecular docking
por: Wang, Shuxiao, et al.
Publicado: (2023)

An Integrated Pharmacology-Based Analysis for Antidepressant Mechanism of Chinese Herbal Formula Xiao-Yao-San
por: Yuan, Naijun, et al.
Publicado: (2020)

Si-Wei-Qing-Gan-Tang Improves Non-Alcoholic Steatohepatitis by Modulating the Nuclear Factor-κB Signal Pathway and Autophagy in Methionine and Choline Deficient Diet-Fed Rats
por: Xiao, Lingyun, et al.
Publicado: (2020)

Effects of Jia-Wei-Xiao-Yao-San on the Peripheral and Lymphatic Pharmacokinetics of Paclitaxel in Rats
por: Hou, Mei-Ling, et al.
Publicado: (2016)

Network Pharmacology and Molecular Docking Analysis on Molecular Mechanism of Qingzi Zhitong Decoction in the Treatment of Ulcerative Colitis
por: Shou, Xintian, et al.
Publicado: (2022)

Gu-Ben-Fang-Xiao Decoction Ameliorated Murine Asthma in Remission Stage by Modulating Microbiota-Acetate-Tregs Axis
por: Dong, Yingmei, et al.
Publicado: (2020)

Ameliorating effect of Erxian decoction combined with Fructus Schisandrae chinensis (Wu Wei Zi) on menopausal sweating and serum hormone profiles in a rat model
por: Wang, Shi Wei, et al.
Publicado: (2016)

Systems pharmacology approach reveals protective mechanisms of Jian-Pi Qing-Chang decoction on ulcerative colitis
por: Chen, You-Lan, et al.
Publicado: (2019)

Yuan-Zhi decoction in the treatment of Alzheimer’s disease: An integrated approach based on chemical profiling, network pharmacology, molecular docking and experimental evaluation
por: Wu, Qiong, et al.
Publicado: (2022)

Network pharmacology, molecular docking, and experimental verification reveal the mechanism of San-Huang decoction in treating acute kidney injury
por: Liu, Jiahui, et al.
Publicado: (2023)

Network Pharmacology-Based Validation of Caveolin-1 as a Key Mediator of Ai Du Qing Inhibition of Drug Resistance in Breast Cancer
por: Wang, Neng, et al.
Publicado: (2018)

Ganghuo Kanggan Decoction in Influenza: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation
por: Lai, Yanni, et al.
Publicado: (2020)

Exploring the Possible Mechanism and Drug Targets of Huang-Qi-Gui-Zhi-Wu-Wu Decoction for the Treatment of Chemotherapy-Induced Peripheral Neuropathy on Network Pharmacology
por: Gu, Jia-lin, et al.
Publicado: (2020)

Integrated Metabolomics and Network Pharmacology Revealed Hong-Hua-Xiao-Yao Tablet’s Effect of Mediating Hormone Synthesis in the Treatment of Mammary Gland Hyperplasia
por: Gao, Ziqing, et al.
Publicado: (2022)

An Ethnobotanical Study on Qīng-Căo-Chá Tea in Taiwan
por: Huang, Shyh-Shyun, et al.
Publicado: (2020)

Integrating Network Pharmacology and Metabolomics Study on Anti-rheumatic Mechanisms and Antagonistic Effects Against Methotrexate-Induced Toxicity of Qing-Luo-Yin
por: Zuo, Jian, et al.
Publicado: (2018)

A Chinese Herbal Formulation, Xiao-Er-An-Shen Decoction, Attenuates Tourette Syndrome, Possibly by Reversing Abnormal Changes in Neurotransmitter Levels and Enhancing Antioxidant Status in Mouse Brain
por: Chen, Jihang, et al.
Publicado: (2019)

Identification of absorbed compounds of Xiao Yao San Jia Wei and pharmacokinetic study in depressed rats by force swimming stress
por: Shan, Chenxiao, et al.
Publicado: (2022)

A Network Pharmacology-Based Identification Study on the Mechanism of Xiao-Xu-Ming Decoction for Cerebral Ischemic Stroke
por: Li, De-Hui, et al.
Publicado: (2020)

Evaluating the Therapeutic Efficacy of Si-Wu-Tang Decoction and Concentrated Extract in Follicular Maldevelopment-Related Menstrual Disorders Through Pharmacokinetic/Pharmacodynamic Studies
por: Lee, Chia-Jung, et al.
Publicado: (2020)

Broad Anti-Viral Capacities of Lian-Hua-Qing-Wen Capsule and Jin-Hua-Qing-Gan Granule and Rational use Against COVID-19 Based on Literature Mining
por: Shi, Mingfei, et al.
Publicado: (2021)

The symbol of spread of modern Western botany into China: Chih-wu hsüeh, an unconventional translation in the late Qing dynasty
por: Zhang, He
Publicado: (2017)

Xiao-Qing-Long-Tang shows preventive effect of asthma in an allergic asthma mouse model through neurotrophin regulation
por: Chang, Ren-Shiu, et al.
Publicado: (2013)

Qing-Re-Xiao-Zheng Formula Modulates Gut Microbiota and Inhibits Inflammation in Mice With Diabetic Kidney Disease
por: Gao, Yabin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_t4d164m4pi87lvl1ol67r1m0dj