Cargando…
Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies
Serologic assays developed for SARS-CoV-2 detect different antibody subtypes and are based on different target antigens. Comparison of the performance of a SARS-CoV-2 Spike-Protein ELISA and the nucleocapsid-based Abbott Architect(TM) SARS-CoV-2 IgG assay indicated that the assays had high concordan...
| Autores principales: | , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320896/ https://www.ncbi.nlm.nih.gov/pubmed/34324576 http://dx.doi.org/10.1371/journal.pone.0255208 |
| _version_ | 1783730722421342208 |
|---|---|
| author | Wadhwa, Ashutosh Yin, Sherry Freeman, Brandi Hershow, Rebecca B. Killerby, Marie Yousaf, Anna R. Lester, Sandra Mills, Lisa Buono, Sean A. Pomeroy, Mary Owusu, Daniel Chu, Victoria T. Tate, Jacqueline E. Bhattacharyya, Sanjib Hall, Patricia Thornburg, Natalie J. Kirking, Hannah L. |
| author_facet | Wadhwa, Ashutosh Yin, Sherry Freeman, Brandi Hershow, Rebecca B. Killerby, Marie Yousaf, Anna R. Lester, Sandra Mills, Lisa Buono, Sean A. Pomeroy, Mary Owusu, Daniel Chu, Victoria T. Tate, Jacqueline E. Bhattacharyya, Sanjib Hall, Patricia Thornburg, Natalie J. Kirking, Hannah L. |
| author_sort | Wadhwa, Ashutosh |
| collection | PubMed |
| description | Serologic assays developed for SARS-CoV-2 detect different antibody subtypes and are based on different target antigens. Comparison of the performance of a SARS-CoV-2 Spike-Protein ELISA and the nucleocapsid-based Abbott Architect(TM) SARS-CoV-2 IgG assay indicated that the assays had high concordance, with rare paired discordant tests results. |
| format | Online Article Text |
| id | pubmed-8320896 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Public Library of Science |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-83208962021-07-31 Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies Wadhwa, Ashutosh Yin, Sherry Freeman, Brandi Hershow, Rebecca B. Killerby, Marie Yousaf, Anna R. Lester, Sandra Mills, Lisa Buono, Sean A. Pomeroy, Mary Owusu, Daniel Chu, Victoria T. Tate, Jacqueline E. Bhattacharyya, Sanjib Hall, Patricia Thornburg, Natalie J. Kirking, Hannah L. PLoS One Research Article Serologic assays developed for SARS-CoV-2 detect different antibody subtypes and are based on different target antigens. Comparison of the performance of a SARS-CoV-2 Spike-Protein ELISA and the nucleocapsid-based Abbott Architect(TM) SARS-CoV-2 IgG assay indicated that the assays had high concordance, with rare paired discordant tests results. Public Library of Science 2021-07-29 /pmc/articles/PMC8320896/ /pubmed/34324576 http://dx.doi.org/10.1371/journal.pone.0255208 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication. |
| spellingShingle | Research Article Wadhwa, Ashutosh Yin, Sherry Freeman, Brandi Hershow, Rebecca B. Killerby, Marie Yousaf, Anna R. Lester, Sandra Mills, Lisa Buono, Sean A. Pomeroy, Mary Owusu, Daniel Chu, Victoria T. Tate, Jacqueline E. Bhattacharyya, Sanjib Hall, Patricia Thornburg, Natalie J. Kirking, Hannah L. Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies |
| title | Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies |
| title_full | Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies |
| title_fullStr | Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies |
| title_full_unstemmed | Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies |
| title_short | Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies |
| title_sort | comparison of the sars-cov-2 spike protein elisa and the abbott architect sars-cov-2 igg nucleocapsid protein assays for detection of antibodies |
| topic | Research Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320896/ https://www.ncbi.nlm.nih.gov/pubmed/34324576 http://dx.doi.org/10.1371/journal.pone.0255208 |
| work_keys_str_mv | AT wadhwaashutosh comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT yinsherry comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT freemanbrandi comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT hershowrebeccab comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT killerbymarie comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT yousafannar comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT lestersandra comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT millslisa comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT buonoseana comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT pomeroymary comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT owusudaniel comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT chuvictoriat comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT tatejacquelinee comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT bhattacharyyasanjib comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT hallpatricia comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT thornburgnataliej comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies AT kirkinghannahl comparisonofthesarscov2spikeproteinelisaandtheabbottarchitectsarscov2iggnucleocapsidproteinassaysfordetectionofantibodies |