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Classification of Microcalcification Clusters in Digital Mammograms Using a Stack Generalization Based Classifier †

This paper presents a machine learning based approach for the discrimination of malignant and benign microcalcification (MC) clusters in digital mammograms. A series of morphological operations was carried out to facilitate the feature extraction from segmented microcalcification. A combination of m...

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Detalles Bibliográficos
Autores principales: Alam, Nashid, R. E. Denton, Erika, Zwiggelaar, Reyer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320960/
https://www.ncbi.nlm.nih.gov/pubmed/34460670
http://dx.doi.org/10.3390/jimaging5090076
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author Alam, Nashid
R. E. Denton, Erika
Zwiggelaar, Reyer
author_facet Alam, Nashid
R. E. Denton, Erika
Zwiggelaar, Reyer
author_sort Alam, Nashid
collection PubMed
description This paper presents a machine learning based approach for the discrimination of malignant and benign microcalcification (MC) clusters in digital mammograms. A series of morphological operations was carried out to facilitate the feature extraction from segmented microcalcification. A combination of morphological, texture, and distribution features from individual MC components and MC clusters were extracted and a correlation-based feature selection technique was used. The clinical relevance of the selected features is discussed. The proposed method was evaluated using three different databases: Optimam Mammography Image Database (OMI-DB), Digital Database for Screening Mammography (DDSM), and Mammographic Image Analysis Society (MIAS) database. The best classification accuracy ([Formula: see text] %) was achieved for OPTIMAM using a stack generalization classifier with 10-fold cross validation obtaining an A [Formula: see text] value equal to [Formula: see text].
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spelling pubmed-83209602021-08-26 Classification of Microcalcification Clusters in Digital Mammograms Using a Stack Generalization Based Classifier † Alam, Nashid R. E. Denton, Erika Zwiggelaar, Reyer J Imaging Article This paper presents a machine learning based approach for the discrimination of malignant and benign microcalcification (MC) clusters in digital mammograms. A series of morphological operations was carried out to facilitate the feature extraction from segmented microcalcification. A combination of morphological, texture, and distribution features from individual MC components and MC clusters were extracted and a correlation-based feature selection technique was used. The clinical relevance of the selected features is discussed. The proposed method was evaluated using three different databases: Optimam Mammography Image Database (OMI-DB), Digital Database for Screening Mammography (DDSM), and Mammographic Image Analysis Society (MIAS) database. The best classification accuracy ([Formula: see text] %) was achieved for OPTIMAM using a stack generalization classifier with 10-fold cross validation obtaining an A [Formula: see text] value equal to [Formula: see text]. MDPI 2019-09-12 /pmc/articles/PMC8320960/ /pubmed/34460670 http://dx.doi.org/10.3390/jimaging5090076 Text en © 2019 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Alam, Nashid
R. E. Denton, Erika
Zwiggelaar, Reyer
Classification of Microcalcification Clusters in Digital Mammograms Using a Stack Generalization Based Classifier †
title Classification of Microcalcification Clusters in Digital Mammograms Using a Stack Generalization Based Classifier †
title_full Classification of Microcalcification Clusters in Digital Mammograms Using a Stack Generalization Based Classifier †
title_fullStr Classification of Microcalcification Clusters in Digital Mammograms Using a Stack Generalization Based Classifier †
title_full_unstemmed Classification of Microcalcification Clusters in Digital Mammograms Using a Stack Generalization Based Classifier †
title_short Classification of Microcalcification Clusters in Digital Mammograms Using a Stack Generalization Based Classifier †
title_sort classification of microcalcification clusters in digital mammograms using a stack generalization based classifier †
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320960/
https://www.ncbi.nlm.nih.gov/pubmed/34460670
http://dx.doi.org/10.3390/jimaging5090076
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