Cargando…
N(6)-methyladenosine promotes induction of ADAR1-mediated A-to-I RNA editing to suppress aberrant antiviral innate immune responses
Among over 150 distinct RNA modifications, N(6)-methyladenosine (m(6)A) and adenosine-to-inosine (A-to-I) RNA editing represent 2 of the most studied modifications on mammalian mRNAs. Although both modifications occur on adenosine residues, knowledge on potential functional crosstalk between these 2...
Autores principales: | Terajima, Hideki, Lu, Mijia, Zhang, Linda, Cui, Qi, Shi, Yanhong, Li, Jianrong, He, Chuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320976/ https://www.ncbi.nlm.nih.gov/pubmed/34324489 http://dx.doi.org/10.1371/journal.pbio.3001292 |
Ejemplares similares
-
RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages
por: Pujantell, Maria, et al.
Publicado: (2017) -
A-to-I RNA editing enzyme ADAR2 regulates light-induced circadian phase-shift
por: Terajima, Hideki, et al.
Publicado: (2018) -
RNA Editing, ADAR1, and the Innate Immune Response
por: Wang, Qingde, et al.
Publicado: (2017) -
A-to-I editing of Malacoherpesviridae RNAs supports the antiviral role of ADAR1 in mollusks
por: Rosani, Umberto, et al.
Publicado: (2019) -
The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA
por: Mannion, Niamh M., et al.
Publicado: (2014)