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Probing the role of the residues in the active site of the transaminase from Thermobaculum terrenum

Creating biocatalysts for (R)-selective amination effectively is highly desirable in organic synthesis. Despite noticeable progress in the engineering of (R)-amine activity in pyridoxal-5’-phosphate-dependent transaminases of fold type IV, the specialization of the activity is still an intuitive tas...

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Detalles Bibliográficos
Autores principales: Bezsudnova, Ekaterina Yu., Nikolaeva, Alena Yu., Bakunova, Alina K., Rakitina, Tatiana V., Suplatov, Dmitry A., Popov, Vladimir O., Boyko, Konstantin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320979/
https://www.ncbi.nlm.nih.gov/pubmed/34324538
http://dx.doi.org/10.1371/journal.pone.0255098